Acepromazine maleate, dopamine, 5-HT1 and 5-HT2 receptor antagonist (ab145170)

Overview

  • Product name

    Acepromazine maleate, dopamine, 5-HT1 and 5-HT2 receptor antagonist
  • Description

    Non-selective dopamine, 5-HT1 and 5-HT2 receptor antagonist. Antipsychotic agent.
  • Biological description

    Non-selective dopamine, 5-HT1 and 5-HT2 receptor antagonist. Antipsychotic agent. Phenothiazine (ab145845) derivative. Shows strong antiadrenergic and weaker peripheral anticholinergic activity. Shows anxiolytic and sedative effects in vivo. Orally active.
  • CAS Number

    3598-37-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Avcikurt AS  et al. Antidepressant and antipsychotic drugs differentially affect PON1 enzyme activity. J Enzyme Inhib Med Chem :1-5 (2014). Read more (PubMed: 24934243) »
  • Karbowski LM  et al. Post-seizure drug treatment in young rats determines clear incremental losses of frontal cortical and hippocampal neurons: the resultant damage is similar to very old brains. Epilepsy Behav 27:18-21 (2013). Read more (PubMed: 23376334) »
  • He S  et al. Ketamine-xylazine-acepromazine compared with isoflurane for anesthesia during liver transplantation in rodents. J Am Assoc Lab Anim Sci 49:45-51 (2010). Read more (PubMed: 20122316) »

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