Product nameAcetyl Coenzyme A Carboxylase peptide
See all Acetyl Coenzyme A Carboxylase proteins and peptides
Amino Acid Sequence
- Recombinant human PRKAA2 + PRKAB2 + PRKAG1 protein (ab126911)
- Recombinant human AMPK alpha 2 + AMPK beta 2 + AMPK gamma 2 protein (ab126916)
- Recombinant human AMPK alpha 1 + AMPK beta 2 +AMPK gamma 2 protein (Active) (ab184883)
- Recombinant human AMPK alpha 1 + AMPK beta 2 + AMPK gamma 3 protein (Active) (ab184885)
- Recombinant human AMPK alpha 2 + beta 1 + gamma 2 protein (ab185258)
- Recombinant human AMPK alpha1 + AMPK beta1 + AMPK gamma1 protein (ab79803)
Our Abpromise guarantee covers the use of ab204881 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ab204881 (Acetyl Coenzyme A Carboxylase peptide) can be utilized as a substrate for the following active protein kinases:
ab184883 (Active human AMPK alpha 1 + AMPK beta 2 +AMPK gamma 2 full length protein)
ab79803 (Active human AMPK alpha1 + AMPK beta1 + AMPK gamma1 full length protein)
ab126911 (Active human PRKAA2 + PRKAB2 + PRKAG1 full length protein)
ab126916 (Active human AMPK alpha 2 full length protein)
ab184885 (Active human AMPK alpha 1 + AMPK beta 2 + AMPK gamma 3 full length protein)
ab185258 (Active human AMPK alpha 2 + beta 1 + gamma 2 full length protein)
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
ReconstitutionDilute peptide in 20mM Tris-HCl, pH 7.5 solution to a final concentration of 1 mg/ml. For optimal storage, aliquot diluted product into smaller quantities and store at recommended temperature.
FunctionCatalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Tissue specificityExpressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.
PathwayLipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Involvement in diseaseAcetyl-CoA carboxylase 1 deficiency
Sequence similaritiesContains 1 ATP-grasp domain.
Contains 1 biotin carboxylation domain.
Contains 1 biotinyl-binding domain.
Contains 1 carboxyltransferase domain.
modificationsPhosphorylation on Ser-1263 is required for interaction with BRCA1.
- Information by UniProt
ab204881 has not yet been referenced specifically in any publications.