Key features and details
- Purity: > 95% HPLC
- Suitable for: Functional Studies, HPLC
Product nameAcetyl Coenzyme A Carboxylase peptide
See all Acetyl Coenzyme A Carboxylase proteins and peptides
Purity> 95 % HPLC.
- Recombinant human PRKAA2 + PRKAB2 + PRKAG1 protein (ab126911)
- Recombinant human AMPK alpha 1 + AMPK beta 2 +AMPK gamma 2 protein (Active) (ab184883)
- Recombinant human AMPK alpha 1 + AMPK beta 2 + AMPK gamma 3 protein (Active) (ab184885)
- Recombinant human AMPK alpha 2 + beta 1 + gamma 2 protein (ab185258)
- Recombinant human AMPK alpha1 + AMPK beta1 + AMPK gamma1 protein (ab79803)
Our Abpromise guarantee covers the use of ab204881 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ab204881 (Acetyl Coenzyme A Carboxylase peptide) can be utilized as a substrate for the following active protein kinases:
ab184883 (Active human AMPK alpha 1 + AMPK beta 2 +AMPK gamma 2 full length protein)
ab79803 (Active human AMPK alpha1 + AMPK beta1 + AMPK gamma1 full length protein)
ab126911 (Active human PRKAA2 + PRKAB2 + PRKAG1 full length protein)
ab126916 (Active human AMPK alpha 2 full length protein)
ab184885 (Active human AMPK alpha 1 + AMPK beta 2 + AMPK gamma 3 full length protein)
ab185258 (Active human AMPK alpha 2 + beta 1 + gamma 2 full length protein)
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
ReconstitutionDilute peptide in 20mM Tris-HCl, pH 7.5 solution to a final concentration of 1 mg/ml. For optimal storage, aliquot diluted product into smaller quantities and store at recommended temperature.
FunctionCatalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Tissue specificityExpressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.
PathwayLipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.
Involvement in diseaseAcetyl-CoA carboxylase 1 deficiency
Sequence similaritiesContains 1 ATP-grasp domain.
Contains 1 biotin carboxylation domain.
Contains 1 biotinyl-binding domain.
Contains 1 carboxyltransferase domain.
modificationsPhosphorylation on Ser-1263 is required for interaction with BRCA1.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab204881 has not yet been referenced specifically in any publications.