Product nameAcetyl-L-carnitine hydrochloride, L-Carnitine derivative
DescriptionL-Carnitine (ab142499) derivative that enables CoA function. Antioxidant.
- Acetyl-L-Carnitine HCL
- Acetylcarnitine hydrochloride
Enables CoA function. Lowers oxidative stress marker levels. Improves mitochondrial function. Blood-brain barrier permeable. Exhibits antidepressant, neuroprotective, analgesic and antinociceptive activities in vivo.
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 25 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Cuccurazzu B et al. Upregulation of mGlu2 Receptors via NF-?B p65 Acetylation Is Involved in the Proneurogenic and Antidepressant Effects of Acetyl-L-Carnitine. Neuropsychopharmacology 38:2220-30 (2013). Read more (PubMed: 23670591) »
- Onofrj M et al. Acetyl-L-carnitine: from a biological curiosity to a drug for the peripheral nervous system and beyond. Expert Rev Neurother 13:925-36 (2013). Read more (PubMed: 23965166) »
- Virmani A et al. Acetyl-L-Carnitine Modulates TP53 and IL10 Gene Expression Induced by 3-NPA Evoked Toxicity in PC12 Cells. Curr Neuropharmacol 9:195-9 (2011). Read more (PubMed: 21886589) »
- Vivoli E et al. Acetyl-L-carnitine increases artemin level and prevents neurotrophic factor alterations during neuropathy. Neuroscience 167:1168-74 (2010). Read more (PubMed: 20302919) »
- Epis R et al. Modulatory effect of acetyl-L-carnitine on amyloid precursor protein metabolism in hippocampal neurons. Eur J Pharmacol 597:51-6 (2008). Read more (PubMed: 18801359) »
- Ghelardini C et al. Acetyl-l-carnitine induces muscarinic antinocieption in mice and rats. Neuropharmacology 43:1180-7 (2002). Read more (PubMed: 12504925) »