Overview

  • Product name

    Acetyl-L-Carnitine, L-carnitine derivative
  • Description

    L-carnitine derivative
  • Biological description

    L-carnitine (ab142499) derivative. Biological carnitine precursor. Enables CoA function. Lowers oxidative stress marker levels. Improves mitochondrial function. Shows chondroprotective and analgesic effects in vivo. Orally active. Blood-brain barrier permeable.
  • Purity

    > 98%
  • CAS Number

    3040-38-8
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (3R)-3-acetyloxy-4-(trimethylazaniumyl)butanoate
  • Molecular weight

    203.24
  • Molecular formula

    C9H17NO4
  • PubChem identifier

    7045767
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=O)OC(CC(=O)[O-])C[N+](C)(C)C
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Bianchi E  et al. Prophylactic role of acetyl-l-carnitine on knee lesions and associated pain in a rat model of osteoarthritis. Life Sci 106:32-9 (2014). Read more (PubMed: 24786526) »
  • Onofrj M  et al. Acetyl-L-carnitine: from a biological curiosity to a drug for the peripheral nervous system and beyond. Expert Rev Neurother 13:925-36 (2013). Read more (PubMed: 23965166) »
  • Lee NY  et al. The acetylcholinesterase inhibitors competitively inhibited an acetyl L-carnitine transport through the blood-brain barrier. Neurochem Res 37:1499-507 (2012). Read more (PubMed: 22359054) »
  • Liu J  et al. Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats. Ann N Y Acad Sci 1033:117-31 (2004). Read more (PubMed: 15591009) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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