Key features and details
- Rabbit polyclonal to ACG
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-ACG antibody
See all ACG primary antibodies
DescriptionRabbit polyclonal to ACG
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human ACG aa 583-628.
Database link: Q5JSL3
- HeLa, Raw264.7 and PC12 whole cell lysates.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab192390 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Our Abpromise guarantee covers the use of ab192390 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent concentration. Predicted molecular weight: 238 kDa.|
FunctionGuanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.
Sequence similaritiesBelongs to the DOCK family.
Contains 1 DHR-1 (CZH-1) domain.
Contains 1 DHR-2 (CZH-2) domain.
Contains 1 PH domain.
DomainThe DHR-2 domain is necessary for the GEF activity.
modificationsPhosphorylated upon DNA damage, probably by ATM or ATR.
- Information by UniProt
- ACG antibody
- Activated Cdc42-associated guanine nucleotide exchange factor antibody
- Dedicator of cytokinesis protein 11 antibody
ab192390 has not yet been referenced specifically in any publications.