- Datasheet
- Specific References
- Protocols
Overview
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Product nameAcinus peptide
See all Acinus proteins and peptides
Description
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NatureSynthetic
Associated products
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Related Products
Specifications
Our Abpromise guarantee covers the use of ab8367 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
Blocking
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FormLiquid
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Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
PBS with 0.1% BSA 0.02% sodium azide pH7.2
General Info
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Alternative names
- ACIN 1
- ACIN1
- ACINU_HUMAN
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FunctionComponent of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
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Tissue specificityUbiquitous.
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Sequence similaritiesContains 1 SAP domain.
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Post-translational
modificationsUndergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form. -
Cellular localizationNucleus.
- Information by UniProt
References
ab8367 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"