Product nameAcinus peptide
See all Acinus proteins and peptides
Our Abpromise guarantee covers the use of ab8368 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
PBS with 0.1% BSA 0.02% sodium azide pH7.2
- ACIN 1
FunctionComponent of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
Sequence similaritiesContains 1 SAP domain.
modificationsUndergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
- Information by UniProt
ab8368 has not yet been referenced specifically in any publications.