Key features and details
- Rabbit polyclonal to ACMSD
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ACMSD antibody
See all ACMSD primary antibodies
DescriptionRabbit polyclonal to ACMSD
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cow, Zebrafish
Recombinant protein fragment containing a sequence corresponding to a region within amino acids 105 and 307 of Human ACMSD.
- Molt-4 and Raji whole cell lysate
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab96081 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 38 kDa.|
FunctionConverts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
PathwaySecondary metabolite metabolism; quinolate metabolism.
Sequence similaritiesBelongs to the ACMSD family.
- Information by UniProt
- 2 amino 3 carboxymuconate 6 semialdehyde decarboxylase antibody
- 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase antibody
- acmsd antibody
ab96081 has been referenced in 1 publication.
- Katsyuba E et al. De novo NAD+ synthesis enhances mitochondrial function and improves health. Nature 563:354-359 (2018). PubMed: 30356218