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The customer kindly phoned to ask about differences between these two products. They are working with duodenum tissues which are very active in iron absorption and are wondering if this high iron contenct will affect the activity assay as well.
Asked on Mar 20 2012
Thank you for contacting us.
I have been in touch with the labs regarding use of ab109712 &ab83459 for duodenumtissue because of its iron aborbence.
In regards to ab109712:Although we have not tested in this tissue type, there have been studies on aconitase and duodenal iron – one paper shows no effect.http://www.ncbi.nlm.nih.gov/pubmed/8541321
In other studies:http://www.ncbi.nlm.nih.gov/pubmed?term=iron%20dudenum%20aconitase Ppresumably the iron is sequestered after absorption preventing significant damage.
In regards to ab83459:We do not think this will be a problem, but we have not tested duodenum.
I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.
Answered on Mar 20 2012