Product nameAnti-Acrolein antibody
See all Acrolein primary antibodies
DescriptionRabbit polyclonal to Acrolein
SpecificityThis antibody targets conjugated acrolein. This antibody does not recognize free acrolein
Tested applicationsSuitable for: IHC-Fr, IHC-Pmore details
Chemical/ Small Molecule corresponding to Acrolein conjugated to Bovine Serum Albumin (BSA).
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferConstituents: 50% Glycerol, ddH20
Concentration information loading...
Our Abpromise guarantee covers the use of ab37110 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-Fr||1/500 - 1/1000. (cryostat)|
|IHC-P||Use at an assay dependent concentration. PubMed: 21953681|
RelevanceAcrolein, a reactive alpha,beta-unsaturated aldehyde, is a common environmental pollutant, a metabolite of the anticancer drug cyclophosphamide, and a byproduct of lipid peroxidation. An increase in acrolein production has been proposed as a marker for Alzheimer's disease, diabetic glomerular lesions, and atherosclerosis. Acrolein is a potent inhibitor of cell proliferation at nonlethal doses and may act through effects on redox-regulated transcription factors. It has been reported that NF-kappaB activation is inhibited by acrolein.
- 2-Propen-1-one antibody
- 2-propenal antibody
- Acraldehyde antibody
This product has been referenced in:
- Lin Y et al. Acrolein Contributes to the Neuropathic Pain and Neuron Damage after Ischemic-Reperfusion Spinal Cord Injury. Neuroscience 384:120-130 (2018). ICC/IF ; Rat . Read more (PubMed: 29852243) »
- Garcia-Gonzalez D et al. Cognition based bTBI mechanistic criteria; a tool for preventive and therapeutic innovations. Sci Rep 8:10273 (2018). Read more (PubMed: 29980750) »