Overview

  • Product name

  • Description

    Rabbit polyclonal to ACSL1
  • Host species

    Rabbit
  • Specificity

    At least three isoforms of ACSL1 are known to exist; ab189939 will detect all three isoforms.
  • Tested applications

    Suitable for: IHC-P, ICC/IF, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human ACSL1 (internal sequence). The exact sequence is proprietary. The peptide corresponds to 18 amino acids. (NCBI Reference Sequence: NP_001986.2)
    Database link: P33121

  • Positive control

    • Human kidney tissue, Human lung tissue and lysate

Applications

Our Abpromise guarantee covers the use of ab189939 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 µg/ml.
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 78 kDa.

Target

  • Function

    Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.
  • Tissue specificity

    Highly expressed in liver, heart, skeletal muscle, kidney and erythroid cells, and to a lesser extent in brain, lung, placenta and pancreas.
  • Sequence similarities

    Belongs to the ATP-dependent AMP-binding enzyme family.
  • Developmental stage

    Expressed during the early stages of erythroid development while expression is very low in reticulocytes and young erythrocytes.
  • Cellular localization

    Mitochondrion outer membrane. Peroxisome membrane. Microsome membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ACS 1 antibody
    • ACS1 antibody
    • ACSL 1 antibody
    • ACSL1 antibody
    • ACSL1_HUMAN antibody
    • Acyl CoA synthetase 1 antibody
    • Acyl CoA synthetase long chain family member 1 antibody
    • Acyl-CoA synthetase 1 antibody
    • FACL 1 antibody
    • FACL 2 antibody
    • FACL1 antibody
    • FACL2 antibody
    • Fatty acid Coenzyme A ligase long chain 1 antibody
    • Fatty acid Coenzyme A ligase long chain 2 antibody
    • LACS 1 antibody
    • LACS 2 antibody
    • LACS antibody
    • LACS1 antibody
    • LACS2 antibody
    • Lignoceroyl CoA synthase antibody
    • Long chain acyl CoA synthetase 1 antibody
    • Long chain acyl CoA synthetase 2 antibody
    • Long chain fatty acid CoA ligase 1 antibody
    • Long chain fatty acid CoA ligase 2 antibody
    • Long chain fatty acid coenzyme A ligase 1 antibody
    • Long-chain acyl-CoA synthetase 1 antibody
    • Long-chain acyl-CoA synthetase 2 antibody
    • Long-chain fatty acid-CoA ligase 2 antibody
    • Long-chain-fatty-acid--CoA ligase 1 antibody
    • Palmitoyl CoA ligase 1 antibody
    • Palmitoyl CoA ligase 2 antibody
    • Palmitoyl-CoA ligase 1 antibody
    • Palmitoyl-CoA ligase 2 antibody
    • Paltimoyl CoA ligase 1 antibody
    see all

Images

  • Lane 1 : Anti-ACSL1 antibody (ab189939) at 1 µg
    Lane 2 : Anti-ACSL1 antibody (ab189939) at 2 µg

    All lanes : Human lung tissue

    Predicted band size: 78 kDa

  • Immunofluorescent analysis of Human lung tissue, staining ACSL1 with ab189939 at 20 µg/ml.

  • Immunohistochemistry of formalin-fixed, paraffin-embedded Human kidney tissue labeling ACSL1 with ab189939 at 5 µg/ml.

References

ab189939 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab189939.
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