Overview

  • Product name

  • Description

    Rabbit polyclonal to ACTG2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Goat, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Saccharomyces cerevisiae, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within C terminal amino acids 325-374 (TMKIKIIAPP ERKYSVWIGG SILASLSTFQ QMWISKPEYD EAGPSIVHRK) of Human ACTG2 (NP_001606).

  • Positive control

    • Human fetal lung lysate

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab133871 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.25 µg/ml. Predicted molecular weight: 42 kDa.

Target

  • Function

    Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
  • Sequence similarities

    Belongs to the actin family.
  • Post-translational
    modifications

    Oxidation of Met-45 and Met-48 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promote actin repolymerization.
    Monomethylation at Lys-85 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.
  • Cellular localization

    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links

  • Alternative names

    • ACT antibody
    • ACTA3 antibody
    • ACTE antibody
    • ACTG2 antibody
    • ACTH_HUMAN antibody
    • Actin antibody
    • Actin gamma 2 smooth muscle enteric antibody
    • Actin gamma enteric smooth muscle antibody
    • Actin like protein antibody
    • ACTL3 antibody
    • ACTSG antibody
    • Alpha actin 3 antibody
    • Alpha-actin-3 antibody
    • Gamma 2 actin antibody
    • Gamma-2-actin antibody
    • gamma-enteric smooth muscle antibody
    • Smooth muscle gamma actin antibody
    • Smooth muscle gamma-actin antibody
    see all

Images

  • Anti-ACTG2 antibody (ab133871) at 0.25 µg/ml + Fetal lung lysate at 10 µg

    Predicted band size: 42 kDa

References

ab133871 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab133871.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up