ACTH (18-39) (human), corticotropin-like intermediate peptide (CLIP) (ab142254)

Overview

  • Product name

    ACTH (18-39) (human), corticotropin-like intermediate peptide (CLIP)
  • Description

    Corticotropin-like intermediate peptide (CLIP)
  • Alternative names

    • Adrenocorticotropic hormone
  • Biological description

    Corticotropin-like intermediate peptide (CLIP). Role in insulin and obesity. Active in vivo.
  • Purity

    > 95%
  • CAS Number

    53917-42-3
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    2465.68
  • Molecular formula

    C112H165N27O36
  • Sequence

    RPVKVYPNGAEDESAEAFPLEF
  • PubChem identifier

    16130980
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)O)NC(=O)CNC(=O)[C@H](CC(=O)N)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CC5=CC=C(C=C5)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C(C)C)NC(=O)C6CCCN6C(=O)[C@H](CCCNC(=N)N)N
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Bonnet C  et al. Influence of a 1-h immobilization stress on sleep and CLIP (ACTH(18-39)) brain contents in adrenalectomized rats. Brain Res 853:323-9 (2000). Read more (PubMed: 10640630) »
  • Bailey CJ & Flatt PR Insulin releasing effects of adrenocorticotropin (ACTH 1-39) and ACTH fragments (1-24 and 18-39) in lean and genetically obese hyperglycaemic (ob/ob) mice. Int J Obes 11:175-81 (1987). Read more (PubMed: 3038765) »
  • Chastrette N & Cespuglio R [Hypnogenic effects of des-acetyl-alpha-MSH and CLIP (ACTH 18-39) in the rat]. C R Acad Sci III 301:527-30 (1985). Read more (PubMed: 3004676) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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