Overview

  • Product name

    Anti-ACTH antibody [AH26] - BSA and Azide free
    See all ACTH primary antibodies
  • Description

    Mouse monoclonal [AH26] to ACTH - BSA and Azide free
  • Host species

    Mouse
  • Specificity

    ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This antibody is specific to Synacthen (aa 1-24 of ACTH); does not react with CLIP (aa 17-39 of ACTH).

  • Tested applications

    Suitable for: Flow Cyt, ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
    Predicted to work with: Sheep, Guinea pig, Cow, a wide range of other species, Macaque monkey
  • Immunogen

    Synthetic peptide aa 1-24.
    Sequence:

    MPRSCCSRSGALLLALLLQASMEV


    Database link: P01189

  • Positive control

    • Normal pituitary gland or pituitary tumor.

Properties

Applications

Our Abpromise guarantee covers the use of ab212734 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.5-1µg for 106 cells.
ICC/IF Use a concentration of 1 - 2 µg/ml.
IHC-P Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance

    ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.
  • Cellular localization

    Secreted
  • Database links

  • Alternative names

    • ACTH antibody
    • Adrenocorticotropic hormone antibody
    • Adrenocorticotropin antibody
    • Alpha melanocyte stimulating hormone antibody
    • alpha-MSH antibody
    • alphaMSH antibody
    • Beta LPH antibody
    • Beta melanocyte stimulating hormone antibody
    • Beta-endorphin antibody
    • beta-MSH antibody
    • CLIP antibody
    • Corticotropin antibody
    • Corticotropin lipotropin antibody
    • Corticotropin-like intermediary peptide antibody
    • Gamma LPH antibody
    • gamma-MSH antibody
    • Lipotropin beta antibody
    • Lipotropin gamma antibody
    • Lipotropin, included antibody
    • LPH antibody
    • Melanocyte-stimulating hormone, included antibody
    • Melanotropin alpha antibody
    • Melanotropin beta antibody
    • Melanotropin gamma antibody
    • Melanotropin, included antibody
    • Met-enkephalin antibody
    • MSH antibody
    • NPP antibody
    • Opiomelanocortin prepropeptide antibody
    • POC antibody
    • POMC antibody
    • Pomc-1 antibody
    • Pomc1 antibody
    • Pomc2 antibody
    • Pro ACTH endorphin antibody
    • Pro opiomelanocortin antibody
    • Pro-opiomelanocortin-alpha antibody
    • Proopiomelanocortin antibody
    • Proopiomelanocortin preproprotein antibody
    • Tetracosactide antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed paraffin-embedded human pituitary gland sections labeling ACTH with ab212734 at 1 µg/mL.

References

ab212734 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab212734.
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