Overview

  • Product name
    Anti-Actin Regulatory Protein CAPG antibody
    See all Actin Regulatory Protein CAPG primary antibodies
  • Description
    Chicken polyclonal to Actin Regulatory Protein CAPG
  • Host species
    Chicken
  • Tested applications
    Suitable for: WB, IHC-Frmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 1-348 of Human Actin Regulatory Protein CAPG

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab14235 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-Fr
  • Application notes
    IHC-Fr: 1/3000 (See PMID 18709641).
    WB: 1/1000. Predicted molecular weight: 39 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
    • Tissue specificity
      Macrophages and macrophage-like cells.
    • Sequence similarities
      Belongs to the villin/gelsolin family.
      Contains 3 gelsolin-like repeats.
    • Post-translational
      modifications
      The N-terminus is blocked.
    • Cellular localization
      Cytoplasm. Nucleus. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • Database links
    • Alternative names
      • Actin capping protein GCAP39 antibody
      • Actin regulatory protein CAP G antibody
      • Actin regulatory protein CAP-G antibody
      • AFCP antibody
      • Capg antibody
      • CAPG_HUMAN antibody
      • Capping actin protein gelsolin like antibody
      • Capping protein (actin filament) gelsolin like antibody
      • Capping protein gelsolin like antibody
      • Epididymis secretory protein Li 66 antibody
      • gCap39 antibody
      • Gelsolin like capping protein antibody
      • HEL S 66 antibody
      • Macrophage capping protein antibody
      • Macrophage-capping protein antibody
      • mbh1 antibody
      • MCP antibody
      • Myc basic motif homolog 1 antibody
      see all

    References

    This product has been referenced in:
    • Partheen K  et al. External validation suggests Integrin beta 3 as prognostic biomarker in serous ovarian adenocarcinomas. BMC Cancer 9:336 (2009). WB ; Human . Read more (PubMed: 19775429) »
    • Partheen K  et al. Four potential biomarkers as prognostic factors in stage III serous ovarian adenocarcinomas. Int J Cancer 123:2130-7 (2008). WB, IHC-Fr ; Human . Read more (PubMed: 18709641) »
    See all 3 Publications for this product

    Customer reviews and Q&As

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Human Tissue lysate - whole (ovarian tumor)
    Specification
    ovarian tumor
    Gel Running Conditions
    Reduced Denaturing
    Blocking step
    Milk as blocking agent for 15 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 4°C

    Abcam user community

    Verified customer

    Submitted Oct 08 2007

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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