Key features and details
- Expression system: Escherichia coli
- Purity: = 95% SDS-PAGE
- Endotoxin level: < 1.000 Eu/µg
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
Product nameActive human Oncostatin M/OSM small molecule
See all Oncostatin M/OSM proteins and peptides
ED(50) of ab268825 was determined by the dose-dependent stimulation of the proliferation of f human TF-1 cells is ≤ 3.0 ng/mL, corresponding to a specific activity of ≥ 2.0 x 10^5 units/mg.
Purity= 95 % SDS-PAGE.
Endotoxin level< 1.000 Eu/µg
Expression systemEscherichia coli
Molecular weight informationSDS-PAGE molecular weight : ~26kDa.
Our Abpromise guarantee covers the use of ab268825 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
ReconstitutionA quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. Upon reconstitution, this cytokine can be stored in working aliquots at 4oC for one month, or at -20oC for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
- Oncostatin M
FunctionGrowth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST).
Sequence similaritiesBelongs to the LIF/OSM family.
- Information by UniProt
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab268825 has not yet been referenced specifically in any publications.