Product nameActive human RHEB peptide
See all RHEB proteins and peptides
Amino Acid Sequence
Our Abpromise guarantee covers the use of ab39861 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Biological activityThis peptide is used for blocking the activity of the Anti-RHEB antibody (ab25873).
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Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.1% BSA, PBS, pH 7.2
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- Ras homolog enriched in brain 2, formerly
- GTP binding protein Rheb
- GTP-binding protein Rheb
FunctionStimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Activates the protein kinase activity of mTORC1. Has low intrinsic GTPase activity.
Tissue specificityUbiquitous. Highest levels observed in skeletal and cardiac muscle.
Sequence similaritiesBelongs to the small GTPase superfamily. Rheb family.
modificationsFarnesylation is important for efficiently activating mTORC1-mediated signaling.
Cellular localizationCell membrane.
- Information by UniProt
ab39861 has not yet been referenced specifically in any publications.