Anti-Activin Receptor Type IIA/ACVR2A antibody (ab96793)
Key features and details
- Rabbit polyclonal to Activin Receptor Type IIA/ACVR2A
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Activin Receptor Type IIA/ACVR2A antibody
See all Activin Receptor Type IIA/ACVR2A primary antibodies -
Description
Rabbit polyclonal to Activin Receptor Type IIA/ACVR2A -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Cow, Zebrafish -
Immunogen
Recombinant fragment corresponding to Human Activin Receptor Type IIA/ACVR2A aa 267-509. (AAH69707)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab96793 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/5000 - 1/20000. Predicted molecular weight: 58 kDa.
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Notes |
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WB
1/5000 - 1/20000. Predicted molecular weight: 58 kDa. |
Target
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Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. -
Sequence similarities
Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Contains 1 protein kinase domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 281598 Cow
- Entrez Gene: 92 Human
- Entrez Gene: 11480 Mouse
- Entrez Gene: 29263 Rat
- Entrez Gene: 553359 Zebrafish
- Omim: 102581 Human
- SwissProt: Q28043 Cow
- SwissProt: P27037 Human
see all -
Alternative names
- Activin A receptor type IIA antibody
- Activin receptor type 2A antibody
- Activin receptor type IIA antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab96793 has been referenced in 3 publications.
- Toms D et al. Automated Hypothesis Generation to Identify Signals Relevant in the Development of Mammalian Cell and Tissue Bioprocesses, With Validation in a Retinal Culture System. Front Bioeng Biotechnol 8:534 (2020). PubMed: 32582664
- Kim KH et al. Human placenta-derived mesenchymal stem cells stimulate ovarian function via miR-145 and bone morphogenetic protein signaling in aged rats. Stem Cell Res Ther 11:472 (2020). PubMed: 33153492
- O'Keeffe GW et al. Region-specific role of growth differentiation factor-5 in the establishment of sympathetic innervation. Neural Dev 11:4 (2016). ICC . PubMed: 26878848