Recombinant
RabMAb

Recombinant Anti-Activin Receptor Type IIA/ACVR2A antibody [EPR7407] (ab134082)

Overview

  • Product name

    Anti-Activin Receptor Type IIA/ACVR2A antibody [EPR7407]
    See all Activin Receptor Type IIA/ACVR2A primary antibodies
  • Description

    Rabbit monoclonal [EPR7407] to Activin Receptor Type IIA/ACVR2A
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Activin Receptor Type IIA/ACVR2A aa 1-100. The exact sequence is proprietary.
    (Peptide available as ab206674)

  • Positive control

    • Human fetal liver, HepG2, HeLa, and K562 cell lysates.
  • General notes

     

     

     This product was previously labelled as Activin Receptor Type IIA

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab134082 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 80 kDa (predicted molecular weight: 58 kDa).Can be blocked with Activin Receptor Type IIA/ACVR2A peptide (ab206674).
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • Function

      On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
    • Sequence similarities

      Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
      Contains 1 protein kinase domain.
    • Cellular localization

      Membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • Activin A receptor type IIA antibody
      • Activin receptor type 2A antibody
      • Activin receptor type IIA antibody
      • Activin receptor type-2A antibody
      • ACTR 2 antibody
      • ACTR IIA antibody
      • ACTR-IIA antibody
      • ACTR2 antibody
      • ACTRII antibody
      • ACTRIIA antibody
      • Acvr 2 antibody
      • Acvr 2A antibody
      • Acvr2 antibody
      • ACVR2A antibody
      • AVR2A_HUMAN antibody
      • OTTHUMP00000197918 antibody
      see all

    Images

    • All lanes : Anti-Activin Receptor Type IIA/ACVR2A antibody [EPR7407] (ab134082) at 1/1000 dilution

      Lane 1 : Human fetal liver lysate
      Lane 2 : HepG2 cell lysate
      Lane 3 : HeLa cell lysate
      Lane 4 : K562 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled Goat anti-rabbit at 1/2000 dilution

      Predicted band size: 58 kDa

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    This product has been referenced in:

    See all 2 Publications for this product

    Customer reviews and Q&As

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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