Key features and details
- Mouse monoclonal [MM0058-6J16] to Activin Receptor Type IIA/ACVR2A
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2
Product nameAnti-Activin Receptor Type IIA/ACVR2A antibody [MM0058-6J16]
See all Activin Receptor Type IIA/ACVR2A primary antibodies
DescriptionMouse monoclonal [MM0058-6J16] to Activin Receptor Type IIA/ACVR2A
SpecificitySpecific for human Activin RIIA. No cross reactivity was found to hActivin RI and RIIB.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Recombinant fragment corresponding to Activin Receptor Type IIA/ACVR2A.
This product was previously labelled as Activin Receptor Type IIA
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab78412 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/100.|
FunctionOn ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
Contains 1 protein kinase domain.
- Information by UniProt
- Activin A receptor type IIA antibody
- Activin receptor type 2A antibody
- Activin receptor type IIA antibody
ab78412 has been referenced in 1 publication.
- Lin TT et al. Follicular localization of growth differentiation factor 8 and its receptors in normal and polycystic ovary syndrome ovaries. Biol Reprod 98:683-694 (2018). PubMed: 29409020