Overview

  • Product name

  • Description

    Rabbit polyclonal to ACY3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IFmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human ACY3 aa 5-319.
    Sequence:

    PVPREPLRRVAVTGGTHGNEMSGVYLARHWLHAPAELQRASFSAVPVLAN PAATSGCRRYVDHDLNRTFTSSFLNSRPTPDDPYEVTRARELNQLLGPKA SGQAFDFVLDLHNTTANMGTCLIAKSSHEVFAMHLCRHLQLQYPELSCQV FLYQRSGEESYNLDSVAKNGLGLELGPQPQGVLRADIFSRMRTLVATVLD FIELFNQGTAFPAFEMEAYRPVGVVDFPRTEAGHLAGTVHPQLQDRDFQP LQPGAPIFQMFSGEDLLYEGESTVYPVFINEAAYYEKGVAFVQTEKFTFT VPAMPALTPAPSPAS


    Database link: Q96HD9

  • Positive control

    • ICC/IF: HepG2 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab237057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/50 - 1/200.

Target

  • Function

    Plays an important role in deacetylating mercapturic acids in kidney proximal tubules.
  • Sequence similarities

    Belongs to the AspA/AstE family. Aspartoacylase subfamily.
  • Cellular localization

    Apical cell membrane. Cytoplasm. Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • AA3 antibody
    • ACY-3 antibody
    • acy3 antibody
    • ACY3_HUMAN antibody
    • Acylase III antibody
    • Aminoacylase 3 antibody
    • Aminoacylase III antibody
    • Aminoacylase-3 antibody
    • ASPA2 antibody
    • Aspartoacylase (aminoacylase) 3 antibody
    • Aspartoacylase 2 antibody
    • Aspartoacylase-2 antibody
    • AW107362 antibody
    • EC 3.5.1.- antibody
    • EC 3.5.1.15 antibody
    • HCBP1 antibody
    • Hepatitis C virus core binding protein 1 antibody
    • Hepatitis C virus core-binding protein 1 antibody
    see all

Images

  • HepG2 (human liver hepatocellular carcinoma cell line) cells stained for ACY3 (green) using ab237057 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488-conjugated goat anti-rabbit IgG (H+L).

References

ab237057 has not yet been referenced specifically in any publications.

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