Validated using a knockout cell line

Recombinant Anti-ADAM10 antibody [EPR5622] (ab124695)

Publishing research using ab124695? Please let us know so that we can cite the reference in this datasheet.

ab124695 has been referenced in 19 publications.

  • Li H  et al. Long non-coding RNA CDKN2B-AS1 reduces inflammatory response and promotes cholesterol efflux in atherosclerosis by inhibiting ADAM10 expression. Aging (Albany NY) 11:1695-1715 (2019). PubMed: 30926762
  • Brummer T  et al. NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease. EMBO Mol Med 11:N/A (2019). PubMed: 30833305
  • Beerli C  et al. Vaccinia virus hijacks EGFR signalling to enhance virus spread through rapid and directed infected cell motility. Nat Microbiol 4:216-225 (2019). PubMed: 30420785
  • Liu L  et al. A cellular complex of BACE1 and ?-secretase sequentially generates Aß from its full-length precursor. J Cell Biol 218:644-663 (2019). PubMed: 30626721
  • Nation DA  et al. Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction. Nat Med 25:270-276 (2019). PubMed: 30643288
  • Vullhorst D & Buonanno A NMDA Receptors Regulate Neuregulin 2 Binding to ER-PM Junctions and Ectodomain Release. Mol Neurobiol 56:8345-8363 (2019). PubMed: 31240601
  • Hou L  et al. PAX2 may induce ADAM10 expression in renal tubular epithelial cells and contribute to epithelial-to-mesenchymal transition. Int Urol Nephrol 50:1729-1741 (2018). PubMed: 30117015
  • Cabron AS  et al. Structural and Functional Analyses of the Shedding Protease ADAM17 in HoxB8-Immortalized Macrophages and Dendritic-like Cells. J Immunol 201:3106-3118 (2018). PubMed: 30355783
  • Ramesh S  et al. SIRT3 activator Honokiol attenuates ß-Amyloid by modulating amyloidogenic pathway. PLoS One 13:e0190350 (2018). PubMed: 29324783
  • Zhao L  et al. Protection against the Neurotoxic Effects of ß-Amyloid Peptide on Cultured Neuronal Cells by Lovastatin Involves Elevated Expression of a7 Nicotinic Acetylcholine Receptors and Activating Phosphorylation of Protein Kinases. Am J Pathol 188:1081-1093 (2018). PubMed: 29341888
  • Sogorb-Esteve A  et al. Levels of ADAM10 are reduced in Alzheimer's disease CSF. J Neuroinflammation 15:213 (2018). PubMed: 30045733
  • Meng T  et al. Tat-haFGF14-154 Upregulates ADAM10 to Attenuate the Alzheimer Phenotype of APP/PS1 Mice through the PI3K-CREB-IRE1a/XBP1 Pathway. Mol Ther Nucleic Acids 7:439-452 (2017). WB ; Mouse . PubMed: 28624220
  • Yan L  et al. Icariside II Effectively Reduces Spatial Learning and Memory Impairments in Alzheimer's Disease Model Mice Targeting Beta-Amyloid Production. Front Pharmacol 8:106 (2017). PubMed: 28337142
  • Luo LD  et al. PLD1 promotes dendritic spine development by inhibiting ADAM10-mediated N-cadherin cleavage. Sci Rep 7:6035 (2017). WB ; Rat . PubMed: 28729535
  • von Hoven G  et al. Dissecting the role of ADAM10 as a mediator of Staphylococcus aureus a-toxin action. Biochem J 473:1929-40 (2016). PubMed: 27147619
  • Chen AC  et al. Physical and functional interaction between the a- and ?-secretases: A new model of regulated intramembrane proteolysis. J Cell Biol 211:1157-76 (2015). PubMed: 26694839
  • Hu T  et al. Increased ADAM10 expression in preeclamptic placentas is associated with decreased expression of hydrogen sulfide production enzymes. Placenta 36:947-50 (2015). PubMed: 26021209
  • Yang C  et al. Enhancement of the nonamyloidogenic pathway by exogenous NGF in an Alzheimer transgenic mouse model. Neuropeptides 48:233-8 (2014). WB ; Mouse . PubMed: 24813062
  • Padro CJ  et al. Adrenergic regulation of IgE involves modulation of CD23 and ADAM10 expression on exosomes. J Immunol 191:5383-97 (2013). PubMed: 24140643

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