Key features and details
- Rabbit polyclonal to ADAMTS14
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ADAMTS14 antibody
DescriptionRabbit polyclonal to ADAMTS14
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human ADAMTS14 (internal sequence). NP_542453.
Database link: Q8WXS8
- Human breast cancer tissue.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab198885 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/25 - 1/100.|
RelevanceADAMTS14 is a member of the ADAMs family of proteinases with 4 thrombospondin (TS)-like domains. These TS motifs are thought to bind ADAMTS14 to the ECM. ADAMTS14 is closest in homology to ADAMTS3, sharing 63% overall identity. ADAMTS14 has a PLAC (Protease and LACunin) domain at the carboxyterminal end, containing a 6 cysteine conserved repeat. The sequence also contains a prohormone-convertase cleavage site (predicted PC cleavage site is the RKRR252 sequence). Several splice variants of ADAMTS-14 have been reported. ADAMTS14 has been shown to be a potential factor in multiple sclerosis (MS), by linkage analysis. ADAMTS14 is expressed in many tissues including lung, brain, liver and placenta.
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ab198885 has been referenced in 1 publication.
- Lin YM et al. Decreased Cytoplasmic Expression of ADAMTS14 Is Correlated with Reduced Survival Rates in Oral Squamous Cell Carcinoma Patients. Diagnostics (Basel) 10:N/A (2020). PubMed: 32102222