Key features and details
- Goat polyclonal to Adenovirus
- Suitable for: ELISA, WB, ICC/IF
- Isotype: IgG
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.1% Sodium azide
Constituent: 0.0268% PBS
Concentration information loading...
PurityIon Exchange Chromatography
Purification notes>95% pure. Sodium sulfate precipitation and ion-exchange chromatography.
Our Abpromise guarantee covers the use of ab36851 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent dilution.|
|WB||Use at an assay dependent dilution.|
|ICC/IF||Use at an assay dependent dilution.|
RelevanceAdenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). Forty-seven known serotypes have been isolated since they were first discovered in 1953 with 3 types known to cause gastroenteritis. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterised by inflammation of conjunctivae and the respiratory tract. The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections. It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated causing disease.
- Adenovirus antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab36851 has been referenced in 3 publications.
- Gu H et al. Bivalent vaccine platform based on ca influenza virus vaccine elicits protective immunity against human adenoviruses. Antiviral Res 153:78-84 (2018). WB . PubMed: 29501624
- Weigert M et al. RIPK3 promotes adenovirus type 5 activity. Cell Death Dis 8:3206 (2017). IHC . PubMed: 29238045
- Tookman LA et al. RAD51 and BRCA2 Enhance Oncolytic Adenovirus Type 5 Activity in Ovarian Cancer. Mol Cancer Res 14:44-55 (2016). WB . PubMed: 26452665