Overview

  • Product name
    Anti-ADI1 antibody
    See all ADI1 primary antibodies
  • Description
    Chicken polyclonal to ADI1
  • Host species
    Chicken
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length native protein (purified), corresponding to amino acids 1-179 of Human ADI1.

  • General notes


Properties

Applications

Our Abpromise guarantee covers the use of ab37877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 21 kDa.

Target

  • Function
    Has aci-reductone dioxygenase (ARD) activity and can function in the 5-methylthioadenosine (MTA) methionine salvage pathway. Down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.
  • Tissue specificity
    Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney.
  • Pathway
    Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.
  • Sequence similarities
    Belongs to the acireductone dioxygenase (ARD) family.
  • Cellular localization
    Cell membrane. Nucleus.
  • Information by UniProt
  • Database links
    • Alternative names
      • 1 2 dihydroxy 3 keto 5 methylthiopentene dioxygenase antibody
      • 1 antibody
      • 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase antibody
      • Aci reductone dioxygenase antibody
      • Acireductone dioxygenase (Fe(2+) requiring) antibody
      • Acireductone dioxygenase (Ni(2+) requiring) antibody
      • Acireductone dioxygenase (Ni(2+)-requiring) antibody
      • Acireductone dioxygenase 1 antibody
      • ADI 1 antibody
      • Adi1 antibody
      • ADI1 antibody antibody
      • APL1 antibody
      • ARD antibody
      • EC 1.13. antibody
      • Fe ARD antibody
      • FLJ10913 antibody
      • HMFT1638 antibody
      • Membrane type 1 matrix metalloproteinase cytoplasmic tail binding protein 1 antibody
      • Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 antibody
      • MT1 MMP cytoplasmic tail binding protein 1 antibody
      • MTCBP 1 antibody
      • MTCBP-1 antibody
      • MTCBP1 antibody
      • MTND_HUMAN antibody
      • Ni-ARD antibody
      • SIPL antibody
      • Submergence induced protein 2 antibody
      • Submergence induced protein 2 homolog antibody
      • Submergence induced protein like factor antibody
      • Submergence-induced protein 2 homolog antibody
      see all

    References

    ab37877 has not yet been referenced specifically in any publications.

    Publishing research using ab37877? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

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    1 Review or Q&A

    10
    Votes: Highest First

    Western blot abreview for Anti-ADI1 antibody

     Good
    Abreviews
    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Human Cell lysate - whole cell (liver)
    Loading amount
    40 µg
    Specification
    liver
    Gel Running Conditions
    Reduced Denaturing
    Blocking step
    Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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    Verified customer

    Submitted Oct 10 2011

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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