Hello. We're improving abcam.com and we'd welcome your feedback.

Hello. We're improving abcam.com and we'd welcome your feedback.

Infomation icon

We haven't added this to the BETA yet

New BETA website

New BETA website

Hello. We're improving abcam.com and we'd welcome your feedback.

Take a look at our BETA site and see what we’ve done so far.

Switch on our new BETA site

Now available

Search and browse selected products

  • A selection of primary antibodies

Purchase these through your usual distributor

In the coming months

  • Additional product types
  • Supporting content
  • Sign in to your account
  • Purchase online

Anti-ADI1 antibody (ab37877)

Reviews (1) Submit a question

Key features and details

  • Chicken polyclonal to ADI1
  • Suitable for: WB
  • Reacts with: Human
  • Isotype: IgY

Overview

  • Product name

    Anti-ADI1 antibody
    See all ADI1 primary antibodies

  • Description

    Chicken polyclonal to ADI1

  • Host species

    Chicken

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Full length native protein (purified), corresponding to amino acids 1-179 of Human ADI1.

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

Applications

The Abpromise guarantee

Our Abpromise guarantee covers the use of ab37877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB (1)
Use at an assay dependent concentration.
Notes
WB
Use at an assay dependent concentration.

Target

  • Function

    Has aci-reductone dioxygenase (ARD) activity and can function in the 5-methylthioadenosine (MTA) methionine salvage pathway. Down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.

  • Tissue specificity

    Detected in heart, colon, lung, stomach, brain, spleen, liver, skeletal muscle and kidney.

  • Pathway

    Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6.

  • Sequence similarities

    Belongs to the acireductone dioxygenase (ARD) family.

  • Cellular localization

    Cell membrane. Nucleus.
  • Information by UniProt

  • Database links

    • Alternative names

      • 1 2 dihydroxy 3 keto 5 methylthiopentene dioxygenase antibody
      • 1 antibody
      • 2-dihydroxy-3-keto-5-methylthiopentene dioxygenase antibody
      • Aci reductone dioxygenase antibody
      • Acireductone dioxygenase (Fe(2+) requiring) antibody
      • Acireductone dioxygenase (Ni(2+) requiring) antibody
      • Acireductone dioxygenase (Ni(2+)-requiring) antibody
      • Acireductone dioxygenase 1 antibody
      • ADI 1 antibody
      • Adi1 antibody
      • ADI1 antibody antibody
      • APL1 antibody
      • ARD antibody
      • EC 1.13. antibody
      • Fe ARD antibody
      • FLJ10913 antibody
      • HMFT1638 antibody
      • Membrane type 1 matrix metalloproteinase cytoplasmic tail binding protein 1 antibody
      • Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 antibody
      • MT1 MMP cytoplasmic tail binding protein 1 antibody
      • MTCBP 1 antibody
      • MTCBP-1 antibody
      • MTCBP1 antibody
      • MTND_HUMAN antibody
      • Ni-ARD antibody
      • SIPL antibody
      • Submergence induced protein 2 antibody
      • Submergence induced protein 2 homolog antibody
      • Submergence induced protein like factor antibody
      • Submergence-induced protein 2 homolog antibody
      see all

    References (0)

    Publishing research using ab37877? Please let us know so that we can cite the reference in this datasheet.

    ab37877 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Show All Reviews Q&A
    Submit a review Submit a question

    Western blot abreview for Anti-ADI1 antibody

     Good
    Abreviews
    abreview image
    Application
    Western blot
    Sample
    Human Cell lysate - whole cell (liver)
    Loading amount
    40 µg
    Specification
    liver
    Gel Running Conditions
    Reduced Denaturing
    Blocking step
    Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Read More
    The reviewer received a reward from Abcam’s Loyalty Program in thanks for submitting this Abreview and for helping the scientific community make better-informed decisions.

    Abcam user community

    Verified customer

    Submitted Oct 10 2011

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com