Key features and details
- Goat polyclonal to ADIPOR1
- Suitable for: WB, IHC-P, ICC
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ADIPOR1 antibody
See all ADIPOR1 primary antibodies
DescriptionGoat polyclonal to ADIPOR1
SpecificityRecognizes Human ADPR1 Receptor. Not likely to cross react with ADPR2.
Tested applicationsSuitable for: WB, IHC-P, ICCmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Chicken, Cow, Cat, Pig, Xenopus laevis
- Human liver tissue and human muscle tissue
This product was previously labelled as Adiponectin Receptor 1
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.1% Sodium azide
Constituents: 0.1% BSA, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab77611 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: 1/250. Recommended buffer: 10 mM KHPO4, 140 mM NaCl, pH 7.2.
WB: 1/1000. Predicted molecular weight: 42 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionReceptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin.
Tissue specificityWidely expressed. Highly expressed in skeletal muscle. Expressed at intermediate level in brain, heart, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine.
Sequence similaritiesBelongs to the ADIPOR family.
DomainThe N-terminus is known to be cytoplasmic while the C-terminus is known to be extracellular.
Cellular localizationMembrane. Localized to the cell membrane and intracellular organelles.
- Information by UniProt
- ACDCR1 antibody
- ADIPO R1 antibody
- Adiponectin receptor protein 1 antibody
ab77611 has been referenced in 4 publications.
- Abdalla BA et al. A Novel Dnmt3a1 Transcript Inhibits Adipogenesis. Front Physiol 9:1270 (2018). PubMed: 30333755
- Basu S et al. Cellular Expression of Cyclooxygenase, Aromatase, Adipokines, Inflammation and Cell Proliferation Markers in Breast Cancer Specimen. PLoS One 10:e0138443 (2015). PubMed: 26431176
- Choi YS et al. Expression of adiponectin, leptin, and their receptors in ovarian endometrioma. Fertil Steril 100:135-41.e1-2 (2013). PubMed: 23579009
- Jeong YJ et al. Expression of leptin, leptin receptor, adiponectin, and adiponectin receptor in ductal carcinoma in situ and invasive breast cancer. J Breast Cancer 14:96-103 (2011). IHC . PubMed: 21847403