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    adiporon-adiponectin-receptor-agonist-ab144867.pdf

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Cardiovascular Lipids / Lipoproteins Adipose Related Acrp
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AdipoRon, Adiponectin receptor agonist (ab144867)

  • Datasheet
  • SDS
  • COA
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Chemical Structure - AdipoRon, Adiponectin receptor agonist (ab144867)

    Key features and details

    • Adiponectin receptor agonist
    • CAS Number: 924416-43-3
    • Purity: > 98%
    • Soluble in ethanol to 100 mM and in DMSO to 100 mM
    • Form / State: Solid
    • Source: Synthetic

    Overview

    • Product name

      AdipoRon, Adiponectin receptor agonist
    • Description

      Adiponectin receptor agonist
    • Biological description

      Adiponectin receptor agonist (KD values are 1.8 and 3.1 μM for AdipoR1 and AdipoR2, respectively). AMPK and PPARα signaling activator. Shows antiobesogenic, antidiabetic and cardioprotective effects in vivo. Orally active.

    • Purity

      > 98%
    • CAS Number

      924416-43-3
    • Chemical structure

      Chemical Structure

    Properties

    • Chemical name

      2-(4-Benzoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamide
    • Molecular weight

      428.52
    • Molecular formula

      C27H28N2O3
    • PubChem identifier

      16307093
    • Storage instructions

      Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
    • Solubility overview

      Soluble in ethanol to 100 mM and in DMSO to 100 mM
    • Handling

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • SMILES

      C1CN(CCC1NC(=O)COC2=CC=C(C=C2)C(=O)C3=CC=CC=C3)CC4=CC=CC=C4
    • Source

      Synthetic

    • Research areas

      • Cardiovascular
      • Lipids / Lipoproteins
      • Adipose Related
      • Acrp
      • Signal Transduction
      • Growth Factors/Hormones
      • Hormones
      • Signal Transduction
      • Metabolism
      • Energy Metabolism
      • Signal Transduction
      • Metabolism
      • Lipid metabolism
      • Cardiovascular
      • Atherosclerosis
      • Lipoprotein metabolism
      • Cardiovascular
      • Atherosclerosis
      • Diabetes associated
      • Cardiovascular
      • Lipids / Lipoproteins
      • Fatty Acids
      • Metabolism
      • Biochemicals
      • Product Range
      • New
      • Biochemicals
      • Chemical Type
      • Biochemicals
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Lipid and lipoprotein metabolism
      • Lipoprotein metabolism
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Lipid and lipoprotein metabolism
      • Fatty acids
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Energy transfer pathways
      • Energy Metabolism
      • Metabolism
      • Types of disease
      • Diabetes
      • Metabolism
      • Types of disease
      • Heart disease
      • Biochemicals
      • Pharmacology
      • Signaling
      • Signal transduction
      • G-Protein related
      • Metabolism
      • Pathways and Processes
      • Redox metabolism
      • Fatty acid oxidation

    Images

    • Chemical Structure - AdipoRon, Adiponectin receptor agonist (ab144867)
      Chemical Structure - AdipoRon, Adiponectin receptor agonist (ab144867)
      2D chemical structure image of ab144867, AdipoRon, Adiponectin receptor agonist

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download
    • COA

    References (1)

    Publishing research using ab144867? Please let us know so that we can cite the reference in this datasheet.

    ab144867 has been referenced in 1 publication.

    • Wang YT  et al. Contribution of transcription factor EB to adipoRon-induced inhibition of arterial smooth muscle cell proliferation and migration. Am J Physiol Cell Physiol 317:C1034-C1047 (2019). PubMed: 31483704

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