Recombinant Anti-Adipose Triglyceride Lipase antibody [EPR3444(2)] - BSA and Azide free (ab239961)


  • Product name

    Anti-Adipose Triglyceride Lipase antibody [EPR3444(2)] - BSA and Azide free
    See all Adipose Triglyceride Lipase primary antibodies
  • Description

    Rabbit monoclonal [EPR3444(2)] to Adipose Triglyceride Lipase - BSA and Azide free
  • Host species

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF or IHC-P
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Adipose Triglyceride Lipase aa 350-450. The exact sequence is proprietary.

  • General notes

    Ab239961 is the carrier-free version of ab109251. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.


    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab239961 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.



Our Abpromise guarantee covers the use of ab239961 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 54 kDa (predicted molecular weight: 55 kDa).
  • Application notes
    Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
  • Target

    • Function

      Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion.
    • Tissue specificity

      Highest expression in adipose tissue. Also detected in heart, skeletal muscle, and portions of the gastrointestinal tract. Detected in normal retina and retinoblastoma cells. Detected in retinal pigment epithelium and, at lower intensity, in the inner segments of photoreceptors and in the ganglion cell layer of the neural retina (at protein level).
    • Pathway

      Glycerolipid metabolism; triacylglycerol degradation.
    • Involvement in disease

      Note=Genetic variations in PNPLA2 may be associated with risk of diabetes mellitus type 2.
      Defects in PNPLA2 are the cause of neutral lipid storage disease with myopathy (NLSDM) [MIM:610717]; also known as neutral lipid storage disease without ichthyosis. NSLDM is a neutral lipid storage disorder (NLSD) with myopathy but without ichthyosis. NLSDs are characterized by the presence of triglyceride-containing cytoplasmic droplets in leukocytes and in other tissues, including bone marrow, skin, and muscle. Individuals with NLSDM did not show obesity, in spite of a defect in triglyceride degradation in fibroblasts and in marked triglyceride storage in liver, muscles, and other visceral cells.
    • Sequence similarities

      Contains 1 patatin domain.
    • Developmental stage

      Induced during differentiation of primary preadipocytes to adipocytes. Expression increased from fetal to adult in retinal pigment epithelium.
    • Cellular localization

      Lipid droplet. Cell membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • 1110001C14Rik antibody
      • Adipose triglyceride lipase antibody
      • ATGL antibody
      • ATGL DESNUTRIN antibody
      • Calcium independent phospholipase A2 antibody
      • Calcium-independent phospholipase A2 antibody
      • Desnutrin antibody
      • EC antibody
      • FP17548 antibody
      • IPLA2 zeta antibody
      • IPLA2-zeta antibody
      • Mutant patatin like phospholipase domain containing 2 antibody
      • Patatin like phospholipase domain containing 2 antibody
      • Patatin-like phospholipase domain-containing protein 2 antibody
      • PEDF R antibody
      • Pigment epithelium derived factor antibody
      • Pigment epithelium-derived factor antibody
      • plpl antibody
      • plpl2 antibody
      • PLPL2_HUMAN antibody
      • Pnpla2 antibody
      • Transport secretion protein 2 antibody
      • Transport secretion protein 2.2 antibody
      • Transport-secretion protein 2 antibody
      • Triglyceride hydrolase antibody
      • TTS 2.2 antibody
      • TTS2 antibody
      • TTS2.2 antibody
      • ZETA antibody
      see all


    ab239961 has not yet been referenced specifically in any publications.

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