Adrenorphin (metorphamide), mu and kappa opioid agonist (ab142708)

Overview

  • Product name

    Adrenorphin (metorphamide), mu and kappa opioid agonist
  • Description

    Potent, selective and endogenous μ and κ opioid agonist
  • Alternative names

    • metorphamide
  • Biological description

    Potent, selective endogenous μ and κ opioid agonist. Shows analgesic and respiratory depressant effects in vivo.
  • Purity

    > 95%
  • CAS Number

    88377-68-8
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    984.20
  • Molecular formula

    C44H69N15O9S
  • Sequence

    YGGFMRRV (Modifications: C-terminal amide)
  • PubChem identifier

    122176
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(C)C(C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCSC)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • McIntosh CH  et al. Characterization of the opioid receptor type mediating inhibition of rat gastric somatostatin secretion. Am J Physiol 259:G922-7 (1990). Read more (PubMed: 1979718) »
  • Miyata A  et al. Adrenorphin immunoreactivity in rat brain. Neuropeptides 5:517-20 (1985). Read more (PubMed: 2860609) »
  • Xu SF  et al. The analgesic and respiratory depressant actions of metorphamide in mice and rabbits. Neuropeptides 6:121-31 (1985). Read more (PubMed: 4000426) »
  • Weber E  et al. Metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. Proc Natl Acad Sci U S A 80:7362-6 (1983). Read more (PubMed: 6316361) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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