Anti-Adropin antibody (ab122800)
Key features and details
- Rabbit polyclonal to Adropin
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Adropin antibody
See all Adropin primary antibodies -
Description
Rabbit polyclonal to Adropin -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
antigen sequence: SADVDSLSES SPNSSPGPCP EKAPPPQKPS HEGSYLLQ, corresponding to amino acids of Human Adropin.
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Positive control
- IHC-P: Human Cerebral cortex, Liver, Kidney and Lung tissues.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab122800 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Involved in the regulation of glucose homestasis and lipid metabolism. -
Tissue specificity
Expressed in liver and brain. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 375704 Human
- SwissProt: Q6UWT2 Human
- Unigene: 522085 Human
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Alternative names
- Adropin antibody
- C9orf165 antibody
- Energy homeostasis associated protein antibody
see all
Images
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ab122800, at 1/200 dilution, staining Adropin in Paraffin-embedded Human kidney tissue by Immunohistochemistry showing cytoplasmic staining of tubules and glomeruli.
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ab122800, at 1/200 dilution, staining Adropin in Paraffin-embedded Human lung tissue by Immunohistochemistry showing cytoplasmic staining in pneumocytes.
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ab122800, at 1/200 dilution, staining Adropin in Paraffin-embedded Human liver tissue by Immunohistochemistry showing cytoplasmic staining in hepatocytes.
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ab122800, at 1/200 dilution, staining Adropin in Paraffin-embedded Human cerebral cortex by Immunohistochemistry showing cytoplasmic staining in neuronal cells and neuropil.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab122800 has been referenced in 4 publications.
- Fujie S et al. Aerobic Exercise Restores Aging-Associated Reductions in Arterial Adropin Levels and Improves Adropin-Induced Nitric Oxide-Dependent Vasorelaxation. J Am Heart Assoc 10:e020641 (2021). PubMed: 33938228
- Muter J et al. The Glycosyltransferase EOGT Regulates Adropin Expression in Decidualizing Human Endometrium. Endocrinology 159:994-1004 (2018). PubMed: 29244071
- Kuloglu T & Aydin S Immunohistochemical expressions of adropin and inducible nitric oxide synthase in renal tissues of rats with streptozotocin-induced experimental diabetes. Biotech Histochem N/A:N/A (2013). PubMed: 23957703
- Aydin S et al. Expression of adropin in rat brain, cerebellum, kidneys, heart, liver, and pancreas in streptozotocin-induced diabetes. Mol Cell Biochem 380:73-81 (2013). PubMed: 23620340