Recombinant Anti-ADX antibody [EPR4629] (ab108257)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4629] to ADX
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
Overview
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Product name
Anti-ADX antibody [EPR4629]
See all ADX primary antibodies -
Description
Rabbit monoclonal [EPR4629] to ADX -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details
Unsuitable for: Flow Cyt or IHC-P -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 0.05% BSA, 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR4629 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab108257 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/10000. Detects a band of approximately 14 kDa (predicted molecular weight: 19 kDa).
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Notes |
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WB
1/1000 - 1/10000. Detects a band of approximately 14 kDa (predicted molecular weight: 19 kDa). |
Target
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Function
Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450. -
Sequence similarities
Belongs to the adrenodoxin/putidaredoxin family.
Contains 1 2Fe-2S ferredoxin-type domain. -
Cellular localization
Mitochondrion matrix. - Information by UniProt
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Database links
- Entrez Gene: 2230 Human
- Entrez Gene: 14148 Mouse
- Entrez Gene: 29189 Rat
- Omim: 103260 Human
- SwissProt: P10109 Human
- SwissProt: P46656 Mouse
- SwissProt: P24483 Rat
- Unigene: 744 Human
see all -
Alternative names
- Adrenal ferredoxin antibody
- Adrenodoxin antibody
- Adrenodoxin, mitochondrial antibody
see all
Images
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All lanes : Anti-ADX antibody [EPR4629] (ab108257) at 1/1000 dilution (Purified)
Lane 1 : A549 (Human lung carcinoma epithelial cell) whole cell lysate
Lane 2 : Mouse kidney lysate
Lane 3 : Rat kidney lysate
Secondary
All lanes : Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/20000 dilution
Predicted band size: 19 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (5)
ab108257 has been referenced in 5 publications.
- Wang L et al. High expression of cuproptosis-related gene FDX1 in relation to good prognosis and immune cells infiltration in colon adenocarcinoma (COAD). J Cancer Res Clin Oncol 149:15-24 (2023). PubMed: 36173462
- Chu B et al. The core genes of cuproptosis assists in discerning prognostic and immunological traits of clear cell renal cell carcinoma. Front Oncol 12:925411 (2022). PubMed: 36212447
- Zhang J et al. FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppression. J Pathol N/A:N/A (2020). PubMed: 32304229
- Zhang Y et al. Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2. Genes Dev N/A:N/A (2017). WB . PubMed: 28747430
- Li J et al. De novo synthesis of steroids and oxysterols in adipocytes. J Biol Chem 289:747-64 (2014). WB . PubMed: 24280213