Overview

  • Product name

  • Description

    Rabbit polyclonal to AF4

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • Host species

    Rabbit
  • Species reactivity


    Predicted to work with: Human
  • Immunogen

    Synthetic peptide corresponding to Human AF4 aa 500-600 conjugated to keyhole limpet haemocyanin.
    (Peptide available as ab32738)

Properties

Target

  • Involvement in disease

    Note=A chromosomal aberration involving AFF1 is associated with acute leukemias. Translocation t(4;11)(q21;q23) with MLL/HRX. The result is a rogue activator protein.
  • Sequence similarities

    Belongs to the AF4 family.
  • Cellular localization

    Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • AF 4 antibody
    • AF 4 protein antibody
    • AF4 antibody
    • AF4-MLL antibody
    • AF4/FMR2 family member 1 antibody
    • AFF 1 antibody
    • AFF1 antibody
    • AFF1_HUMAN antibody
    • ALL1 fused gene from chromosome 4 antibody
    • ALL1-fused gene from chromosome 4 protein antibody
    • FEL antibody
    • MGC134969 antibody
    • MLL/AF4 antibody
    • MLLT2 antibody
    • myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila); translocated to, 2 antibody
    • MYELOID/LYMPHOID OR MIXED LINEAGE LEUKEMIA TRANSLOCATED TO 2; MLLT2 antibody
    • PBM1 antibody
    • Pre B cell monocytic leukemia partner 1 antibody
    • Protein AF-4 antibody
    • Protein FEL antibody
    • Proto-oncogene AF4 antibody
    see all

References

This product has been referenced in:

  • Yadav D  et al. Multivalent Role of Human TFIID in Recruiting Elongation Components at the Promoter-Proximal Region for Transcriptional Control. Cell Rep 26:1303-1317.e7 (2019). Read more (PubMed: 30699356) »
  • Ghosh K  et al. Positive Regulation of Transcription by Human ZMYND8 through Its Association with P-TEFb Complex. Cell Rep 24:2141-2154.e6 (2018). Read more (PubMed: 30134174) »
See all 7 Publications for this product

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