Anti-AGAP1 antibody (ab151480)

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Overview

  • Product name

    Anti-AGAP1 antibody
    See all AGAP1 primary antibodies

  • Description

    Rabbit polyclonal to AGAP1

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WB, IHC-Pmore details

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Xenopus laevis

  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 24-261 of Human AGAP1 (Uniprot: Q9UPQ3-3).

  • Positive control

    • MCF7 whole cell lysate; MDAMB231 xenograft tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab151480 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 45 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system.

  • Tissue specificity

    Widely expressed.

  • Sequence similarities

    Belongs to the centaurin gamma-like family.
    Contains 2 ANK repeats.
    Contains 1 Arf-GAP domain.
    Contains 1 PH domain.

  • Domain

    The PH domain mediates AP-3 binding.

  • Post-translational
    modifications

    Phosphorylated on tyrosines.

  • Cellular localization

    Cytoplasm. Associates with the endocytic compartment.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • AGAP 1 antibody
    • AGAP-1 antibody
    • Agap1 antibody
    • AGAP1_HUMAN antibody
    • Arf GAP with GTP binding proteinlike ANK repeat and PH domains 1 antibody
    • Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 antibody
    • ArfGAP with GTPase domain ankyrin repeat and PH domain 1 antibody
    • Centaurin gamma 2 antibody
    • Centaurin-gamma-2 antibody
    • CENTG2 antibody
    • Cnt-g2 antibody
    • GGAP 1 antibody
    • GGAP1 antibody
    • GTP binding and GTPase activating protein 1 antibody
    • GTP-binding and GTPase-activating protein 1 antibody
    • KIAA1099 antibody
    • MGC71657 antibody
    see all

Images

  • Western blot - Anti-AGAP1 antibody (ab151480)
    Western blot - Anti-AGAP1 antibody (ab151480)
    Anti-AGAP1 antibody (ab151480) at 1/1000 dilution + MCF-7 whole cell lysate at 30 µg

    Predicted band size: 45 kDa



    10% SDS-PAGE
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGAP1 antibody (ab151480)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-AGAP1 antibody (ab151480)
    Immunohistochemical analysis of paraffin embedded MDAMB231 xenograft tissue, labeling AGAP1 with ab151480 at 1/250 dilution.

References

ab151480 has not yet been referenced specifically in any publications.

Publishing research using ab151480? Please let us know so that we can cite the reference in this datasheet.

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