Overview

  • Product name

    AGK2, sirtuin2 (SIRT2) inhibitor
  • Description

    Selective reversible cell-permeable sirtuin2 (SIRT2) inhibitor
  • Biological description

    Selective reversible cell-permeable sirtuin2 (SIRT2) inhibitor (IC50 = 3.5 μM). Protects dopamine neurons from α-synuclein toxicity in vivo. Orally active.
  • Purity

    > 95%
  • CAS Number

    304896-28-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Outeiro TF  et al. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science 317:516-9 (2007). Read more (PubMed: 17588900) »

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