Overview

  • Product name

    Anti-AGO3 antibody [EPR9576]
    See all AGO3 primary antibodies
  • Description

    Rabbit monoclonal [EPR9576] to AGO3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC/IF,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    corresponding to Human AGO3.
    Database link: Q9H9G7

  • Positive control

    • Human fetal brain and fetal kidney lysates.
  • General notes

     This product was previously labelled as Argonaute 3 / eIF2C 3

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab154844 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 97 kDa.
  • Application notes
    Is unsuitable for ICC/IF,IHC-P or IP.
  • Target

    • Function

      Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.
    • Sequence similarities

      Belongs to the argonaute family. Ago subfamily.
      Contains 1 PAZ domain.
      Contains 1 Piwi domain.
    • Cellular localization

      Cytoplasm > P-body.
    • Information by UniProt
    • Database links

    • Alternative names

      • 5730550L01Rik antibody
      • Ago 3 antibody
      • Ago3 antibody
      • AGO3_HUMAN antibody
      • argonaute 3 antibody
      • Argonaute3 antibody
      • eIF 2C 3 antibody
      • eIF-2C 3 antibody
      • eIF2C 3 antibody
      • Eif2c3 antibody
      • EIF2C3 protein antibody
      • Eukaryotic translation initiation factor 2C 3 antibody
      • Eukaryotic translation initiation factor 2C3 antibody
      • FLJ12765 antibody
      • hAgo3 antibody
      • MGC86946 antibody
      • Protein argonaute-3 antibody
      see all

    Images

    • All lanes : Anti-AGO3 antibody [EPR9576] (ab154844) at 1/1000 dilution

      Lane 1 : Human fetal brain lysate
      Lane 2 : Human fetal kidney lysate

      Lysates/proteins at 10 µl/ml buffer per lane.

      Predicted band size: 97 kDa

    References

    This product has been referenced in:

    • Voutila J  et al. Development and Mechanism of Small Activating RNA Targeting CEBPA, a Novel Therapeutic in Clinical Trials for Liver Cancer. Mol Ther 25:2705-2714 (2017). Read more (PubMed: 28882451) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab154844.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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