Overview

  • Product name

  • Description

    Rabbit polyclonal to AGPAT3
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human AGPAT3 aa 121-170. The exact sequence is proprietary.
    Sequence:

    LAKKELLYVP LIGWTWYFLE IVFCKRKWEE DRDTVVEGLR RLSDYPEYMW


    Database link: Q9NRZ7

  • Positive control

    • WB - K562 cell lysate IHC-P- Human kidney tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab211435 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 43 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
  • Pathway

    Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.
  • Sequence similarities

    Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
  • Domain

    The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
  • Cellular localization

    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma antibody
    • 1-acylglycerol-3-phosphate O-acyltransferase 3 antibody
    • 1-AGP acyltransferase 3 antibody
    • 1-AGPAT 3 antibody
    • acyltransferase gamma antibody
    • AGPAT3 antibody
    • LPAAT-gamma antibody
    • Lysophosphatidic acid acyltransferase gamma antibody
    • PLCC_HUMAN antibody
    • UNQ759/PRO1490 antibody
    see all

Images

  • All lanes : Anti-AGPAT3 antibody (ab211435) at 1/500 dilution

    Lane 1 : K562 cell lysate
    Lane 2 : K562 cell lysate with Synthetic peptide from Human AGPAT3 (aa121-170)

    Predicted band size: 43 kDa

  • Immunohistchemical analysis of formalin fixed, paraffin embedded Human kidney tissue labeling AGPAT3 with ab211435 at 10 µg/ml.

References

ab211435 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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