Key features and details
- Rabbit polyclonal to AGXT
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-AGXT antibody
See all AGXT primary antibodies
DescriptionRabbit polyclonal to AGXT
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Cat
- HeLa cell lysate and Human fetal liver tissue lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.4
Preservative: 0.05% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine)
PBS without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab183087 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/200 - 1/1000. Predicted molecular weight: 43 kDa.|
Involvement in diseaseDefects in AGXT are the cause of hyperoxaluria primary type 1 (HP1) [MIM:259900]; also known as primary hyperoxaluria type I (PH1) and oxalosis I. HP1 is a rare autosomal recessive inborn error of glyoxylate metabolism characterized by increased excretion of oxalate and glycolate, and the progressive accumulation of insoluble calcium oxalate in the kidney and urinary tract.
Sequence similaritiesBelongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
Cellular localizationPeroxisome. Mitochondrion matrix. Except in some HP1 patients where AGT is found in the mitochondrial matrix.
- Information by UniProt
- AGT antibody
- AGT1 antibody
- Agxt antibody
All lanes : Anti-AGXT antibody (ab183087) at 1/400 dilution
Lane 1 : HeLa cell lysate
Lane 2 : Human fetal liver tissue lysate
Lysates/proteins at 40 µg per lane.
All lanes : Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Developed using the ECL technique.
Predicted band size: 43 kDa
Exposure time: 2 minutes
ab183087 has not yet been referenced specifically in any publications.