Recombinant Anti-AIF antibody [E20] - Mitochondrial Marker (ab32516)

Rabbit recombinant monoclonal AIF antibody [E20]. Validated in WB, IP, IHC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Human. Cited in 25 publication(s). Independently reviewed in 4 review(s).

Publishing research using ab32516? Please let us know so that we can cite the reference in this datasheet.

ab32516 has been referenced in 32 publications.

  • Chen Y  et al. Photoreceptor degeneration in microphthalmia (Mitf) mice: partial rescue by pigment epithelium-derived factor. Dis Model Mech 12:N/A (2019). PubMed: 30651300
  • Guida M  et al. Parkin Interacts with Apoptosis-Inducing Factor and Interferes with Its Translocation to the Nucleus in Neuronal Cells. Int J Mol Sci 20:N/A (2019). PubMed: 30754623
  • Keuss MJ  et al. Unanchored tri-NEDD8 inhibits PARP-1 to protect from oxidative stress-induced cell death. EMBO J 38:N/A (2019). PubMed: 30804002
  • Qin QJ  et al. Rhynchophylline ameliorates myocardial ischemia/reperfusion injury through the modulation of mitochondrial mechanisms to mediate myocardial apoptosis. Mol Med Rep 19:2581-2590 (2019). PubMed: 30720139
  • Timper K  et al. Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity. Cell Rep 25:383-397.e10 (2018). PubMed: 30304679
  • McCormack K The cardioprotective effect of dexrazoxane (Cardioxane) is consistent with sequestration of poly(ADP-ribose) by self-assembly and not depletion of topoisomerase 2B. Ecancermedicalscience 12:889 (2018). PubMed: 30792806
  • Liu S  et al. Gastrodin alleviates glucocorticoid induced osteoporosis in rats via activating the Nrf2 signaling pathways. Oncotarget 9:11528-11540 (2018). PubMed: 29545917
  • Wang J  et al. Metabotropic glutamate receptor subtype 2 is a cellular receptor for rabies virus. PLoS Pathog 14:e1007189 (2018). PubMed: 30028877
  • Lehmer C  et al. A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS. EMBO Mol Med 10:N/A (2018). WB . PubMed: 29789341
  • Pittala S  et al. Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide. Neoplasia 20:594-609 (2018). WB, IHC-P ; Mouse . PubMed: 29747160
  • Che Z  et al. Targeting CAND1 promotes caspase-8/RIP1-dependent apoptosis in liver cancer cells. Am J Transl Res 10:1357-1372 (2018). PubMed: 29887951
  • Trepiana J  et al. Unraveling the in vitro antitumor activity of Vismia baccifera against HepG2: role of hydrogen peroxide. Heliyon 4:e00675 (2018). PubMed: 30003166
  • Liu J  et al. Nutrient deprivation induces apoptosis of nucleus pulposus cells via activation of the BNIP3/AIF signalling pathway. Mol Med Rep 16:7253-7260 (2017). PubMed: 28944876
  • Khacho M  et al. Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis. Hum Mol Genet 26:3327-3341 (2017). PubMed: 28595361
  • ElMokh O  et al. Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo. Oncotarget 8:24604-24620 (2017). WB ; Mouse . PubMed: 28445948
  • Wang Y  et al. Tilianin Post-Conditioning Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondrial Protection and Inhibition of Apoptosis. Med Sci Monit 23:4490-4499 (2017). PubMed: 28922345
  • Fan WY  et al. The cytotoxic effect of oxybuprocaine on human corneal epithelial cells by inducing cell cycle arrest and mitochondria-dependent apoptosis. Hum Exp Toxicol N/A:N/A (2016). PubMed: 27590991
  • Hayakawa K  et al. Transfer of mitochondria from astrocytes to neurons after stroke. Nature 535:551-5 (2016). PubMed: 27466127
  • El Zaoui I  et al. Glucocorticoids exert direct toxicity on microvasculature: analysis of cell death mechanisms. Toxicol Sci 143:441-53 (2015). PubMed: 25447644
  • Chen Y  et al. Critical Role of the Neonatal Fc Receptor (FcRn) in the Pathogenic Action of Antimitochondrial Autoantibodies Synergizing with Anti-desmoglein Autoantibodies in Pemphigus Vulgaris. J Biol Chem 290:23826-37 (2015). PubMed: 26260795
  • Donis-Maturano L  et al. Prolonged exposure to neutrophil extracellular traps can induce mitochondrial damage in macrophages and dendritic cells. Springerplus 4:161 (2015). PubMed: 25883887
  • Zong L  et al. Mutations in apoptosis-inducing factor cause X-linked recessive auditory neuropathy spectrum disorder. J Med Genet 52:523-31 (2015). IF . PubMed: 25986071
  • Tang Y  et al. Quantitative proteomic analysis of HER2 normal and overexpressing MCF-7 breast cancer cells revealed proteomic changes accompanied with HER2 gene amplification. J Proteomics 91C:200-209 (2013). Human . PubMed: 23851309
  • Kim TW  et al. (ADP-ribose) polymerase 1 and AMP-activated protein kinase mediate progressive dopaminergic neuronal degeneration in a mouse model of Parkinson's disease. Cell Death Dis 4:e919 (2013). IHC-FoFr ; Mouse . PubMed: 24232095
  • Fowler AK  et al. Alcohol-induced One-carbon Metabolism Impairment Promotes Dysfunction of DNA Base Excision Repair in Adult Brain. J Biol Chem 287:43533-42 (2012). IHC-Fr ; Mouse . PubMed: 23118224
  • Rios EC  et al. Volume replacement with saline solutions during pancreatitis in rats and the hepatic profiles of apoptotic proteins and heat-shock proteins. Rev Bras Ter Intensiva 24:326-33 (2012). WB . PubMed: 23917928
  • Smith SJ  et al. Pediatric high-grade glioma: identification of poly(ADP-ribose) polymerase as a potential therapeutic target. Neuro Oncol 13:1171-7 (2011). PubMed: 21849329
  • Fang X  et al. Perfluorononanoic acid-induced apoptosis in rat spleen involves oxidative stress and the activation of caspase-independent death pathway. Toxicology 267:54-9 (2010). WB ; Rat . PubMed: 19878704
  • Huang R  et al. The multikinase inhibitor sorafenib induces caspase-dependent apoptosis in PC-3 prostate cancer cells. Asian J Androl 12:527-34 (2010). PubMed: 20473320
  • Vosler PS  et al. Calcium dysregulation induces apoptosis-inducing factor release: cross-talk between PARP-1- and calpain-signaling pathways. Exp Neurol 218:213-20 (2009). WB . PubMed: 19427306
  • Yu SW  et al. Outer mitochondrial membrane localization of apoptosis-inducing factor: mechanistic implications for release. ASN Neuro 1: (2009). IHC-FoFr ; Mouse . PubMed: 19863494
  • Keilhoff G  et al. Minocycline protects Schwann cells from ischemia-like injury and promotes axonal outgrowth in bioartificial nerve grafts lacking Wallerian degeneration. Exp Neurol 212:189-200 (2008). ICC/IF ; Rat . PubMed: 18501894

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