Key features and details
- Rabbit polyclonal to AIFM3
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-AIFM3 antibody
See all AIFM3 primary antibodies
DescriptionRabbit polyclonal to AIFM3
Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to 16 amino acids from near the amino terminus of human AIFM3 (Q96NN9).
- AIFM3 mouse tissue lysates and human brain tissue.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 2.68% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106359 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 67 kDa.|
|IHC-P||Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval via the microwave method before commencing with IHC staining protocol.|
FunctionInduces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Tissue specificityUbiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
Sequence similaritiesBelongs to the FAD-dependent oxidoreductase family.
Contains 1 Rieske domain.
DomainThe Rieske domain induces apoptosis.
Cellular localizationMitochondrion. Does not translocate to the nucleus upon induction of apoptosis.
- Information by UniProt
- AIFL antibody
- Aifm3 antibody
- AIFM3_HUMAN antibody
Immunofluorescence of AIFM3 in Human brain tissue with ab106359 at 20 ug/mL.
Lane 1 : Anti-AIFM3 antibody (ab106359) at 1 µg/ml
Lane 2 : Anti-AIFM3 antibody (ab106359) at 2 µg/ml
All lanes : Mouse brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 67 kDa
Immunohistochemical staining of human brain tissue using ab106359 at 2.5 µg
ab106359 has not yet been referenced specifically in any publications.