Overview

  • Product name

  • Description

    Goat polyclonal to AIMP3/p18
  • Host species

    Goat
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Pig, Chimpanzee, Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human AIMP3/p18 aa 17-29 (internal sequence) (Cysteine residue). Near N-terminus (NP_004271.1).
    Sequence:

    SKGNKYSAQGERQ


    Database link: O43324

  • Positive control

    • HepG2 and K562 cell lysates; Human pancreas tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.02% Sodium azide
    Constituents: 0.5% BSA, 99% Tris buffered saline
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab191545 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 19 kDa (predicted molecular weight: 19 kDa).
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function

    Positive modulator of ATM response to DNA damage.
  • Tissue specificity

    Down-regulated in various cancer tissues.
  • Sequence similarities

    Contains 1 GST C-terminal domain.
  • Cellular localization

    Cytoplasm. Nucleus. Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage.
  • Information by UniProt
  • Database links

  • Alternative names

    • AIMP 3 antibody
    • AIMP3 antibody
    • Aminoacyl tRNA synthetase complex interacting multifunctional protein 3 antibody
    • Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3 antibody
    • ARS interacting multifunctional protein 3 antibody
    • EEF1E1 antibody
    • Elongation factor p18 antibody
    • Eukaryotic translation elongation factor 1 epsilon 1 antibody
    • Eukaryotic translation elongation factor 1 epsilon-1 antibody
    • Homolog of rat elongation factor p18 antibody
    • MCA3_HUMAN antibody
    • Multisynthase complex auxiliary component p18 antibody
    • Multisynthetase complex auxiliary component p18 antibody
    • p18 antibody
    • p18 component of aminoacyl tRNA synthetase complex antibody
    see all

Images

  • Anti-AIMP3/p18 antibody (ab191545) at 0.1 µg/ml + K562 cell lysate (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 19 kDa
    Observed band size: 19 kDa



    Primary incubation was 1 hour.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas tissue labeling AIMP3/p18 with ab191545 at 5 µg/ml.

References

ab191545 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab191545.
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