Overview

  • Product name

  • Description

    Rabbit polyclonal to AIP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human AIP1 aa 1308-1455.
    Sequence:

    QRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGLAAADA ADAARAGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAG ARAGPRPGPRPPGGAPARKAAVAPGPWKVPGSDKLPSVLKPGASAASR


    Database link: Q86UL8

  • Positive control

    • IHC-P: Human brain tissue. ICC/IF: A549 cells.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.03% Proclin
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    Purity >95%.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab238688 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/50 - 1/200.
IHC-P 1/20 - 1/200.

Target

  • Function

    Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation.
  • Tissue specificity

    Specifically expressed in brain.
  • Sequence similarities

    Belongs to the MAGUK family.
    Contains 1 guanylate kinase-like domain.
    Contains 6 PDZ (DHR) domains.
    Contains 2 WW domains.
  • Cellular localization

    Cell junction > synapse > synaptosome. Cell membrane. Membrane-associated in synaptosomes.
  • Information by UniProt
  • Database links

  • Alternative names

    • Activin receptor interacting protein 1 antibody
    • Acvri1 antibody
    • Acvrinp1 antibody
    • ACVRIP1 antibody
    • AIP 1 antibody
    • Aip-1 antibody
    • ARIP1 antibody
    • Atrophin 1 interacting protein 1 antibody
    • Atrophin 1 interacting protein A antibody
    • Atrophin-1-interacting protein 1 antibody
    • Atrophin-1-interacting protein A antibody
    • KIAA0705 antibody
    • MAGI-2 antibody
    • MAGI2 antibody
    • MAGI2_HUMAN antibody
    • Membrane associated guanylate kinase 2 antibody
    • Membrane associated guanylate kinase inverted 2 antibody
    • Membrane associated guanylate kinase WW and PDZ domain containing 2 antibody
    • Membrane associated guanylate kinase WW and PDZ domain containing protein 2 antibody
    • Membrane-associated guanylate kinase antibody
    • Membrane-associated guanylate kinase inverted 2 antibody
    • S SCAM antibody
    • SSCAM antibody
    • WW and PDZ domain-containing protein 2 antibody
    see all

Images

  • Paraffin-embedded human brain tissue stained for AIP1 using ab238688 at 1/100 dilution in immunohistochemical analysis.

  • A549 (human lung carcinoma cell line) cells stained for AIP1 (green) using ab238688 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).

References

ab238688 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab238688.
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