Anti-AIP1 antibody (ab97343)
Key features and details
- Rabbit polyclonal to AIP1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-AIP1 antibody
See all AIP1 primary antibodies -
Description
Rabbit polyclonal to AIP1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide, corresponding to a sequence within amino acids 1393-1455 of Human AIP1 (NP_036433).
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Positive control
- A431, H1299, HeLa, HepG2 and Raji cells
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 89.99% PBS, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab97343 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/3000. Predicted molecular weight: 159 kDa.
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Notes |
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WB
1/500 - 1/3000. Predicted molecular weight: 159 kDa. |
Target
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Function
Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. -
Tissue specificity
Specifically expressed in brain. -
Sequence similarities
Belongs to the MAGUK family.
Contains 1 guanylate kinase-like domain.
Contains 6 PDZ (DHR) domains.
Contains 2 WW domains. -
Cellular localization
Cell junction > synapse > synaptosome. Cell membrane. Membrane-associated in synaptosomes. - Information by UniProt
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Database links
- Entrez Gene: 9863 Human
- Omim: 606382 Human
- SwissProt: Q86UL8 Human
- Unigene: 603842 Human
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Alternative names
- Activin receptor interacting protein 1 antibody
- Acvri1 antibody
- Acvrinp1 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (3)
ab97343 has been referenced in 3 publications.
- Yao X et al. Endoplasmic reticulum stress-induced exosomal miR-27a-3p promotes immune escape in breast cancer via regulating PD-L1 expression in macrophages. J Cell Mol Med 24:9560-9573 (2020). PubMed: 32672418
- Jauregi-Miguel A et al. MAGI2 Gene Region and Celiac Disease. Front Nutr 6:187 (2019). PubMed: 31921880
- Zhang H et al. Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p/VEGFA Pathway. Front Neurosci 12:644 (2018). PubMed: 30294253