Overview

  • Product name

  • Description

    Rabbit polyclonal to AIP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a sequence within amino acids 1393-1455 of Human AIP1 (NP_036433).

  • Positive control

    • A431, H1299, HeLa, HepG2 and Raji cells

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: PBS, 10% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab97343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 159 kDa.

Target

  • Function

    Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation.
  • Tissue specificity

    Specifically expressed in brain.
  • Sequence similarities

    Belongs to the MAGUK family.
    Contains 1 guanylate kinase-like domain.
    Contains 6 PDZ (DHR) domains.
    Contains 2 WW domains.
  • Cellular localization

    Cell junction > synapse > synaptosome. Cell membrane. Membrane-associated in synaptosomes.
  • Information by UniProt
  • Database links

  • Alternative names

    • Activin receptor interacting protein 1 antibody
    • Acvri1 antibody
    • Acvrinp1 antibody
    • ACVRIP1 antibody
    • AIP 1 antibody
    • Aip-1 antibody
    • ARIP1 antibody
    • Atrophin 1 interacting protein 1 antibody
    • Atrophin 1 interacting protein A antibody
    • Atrophin-1-interacting protein 1 antibody
    • Atrophin-1-interacting protein A antibody
    • KIAA0705 antibody
    • MAGI-2 antibody
    • MAGI2 antibody
    • MAGI2_HUMAN antibody
    • Membrane associated guanylate kinase 2 antibody
    • Membrane associated guanylate kinase inverted 2 antibody
    • Membrane associated guanylate kinase WW and PDZ domain containing 2 antibody
    • Membrane associated guanylate kinase WW and PDZ domain containing protein 2 antibody
    • Membrane-associated guanylate kinase antibody
    • Membrane-associated guanylate kinase inverted 2 antibody
    • S SCAM antibody
    • SSCAM antibody
    • WW and PDZ domain-containing protein 2 antibody
    see all

Images

  • Anti-AIP1 antibody (ab97343) at 1/1000 dilution + Raji whole cell lysate at 30 µg

    Predicted band size: 159 kDa



    7.5% SDS-PAGE.

References

This product has been referenced in:

  • Zhang H  et al. Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p/VEGFA Pathway. Front Neurosci 12:644 (2018). Read more (PubMed: 30294253) »
See 1 Publication for this product

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