Key features and details
- Rabbit polyclonal to AIPL1
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-AIPL1 antibody
See all AIPL1 primary antibodies
DescriptionRabbit polyclonal to AIPL1
Tested applicationsSuitable for: WB, ICC/IF, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
A 17 amino acid synthetic peptide near the carboxy terminus of human AIPL1 (NP_055151).
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab79039 was purified by affinity chromatography via a peptide column
Our Abpromise guarantee covers the use of ab79039 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 44 kDa.|
|ICC/IF||Use a concentration of 20 µg/ml.|
|IHC-P||Use at an assay dependent concentration.|
FunctionMay be important in protein trafficking and/or protein folding and stabilization.
Tissue specificityHighly expressed in retina. Specifically localized to the developing photoreceptor layer and within the photoreceptors of the adult retina.
Involvement in diseaseDefects in AIPL1 are the cause of Leber congenital amaurosis type 4 (LCA4) [MIM:604393]. LCA designates a clinically and genetically heterogeneous group of childhood retinal degenerations, generally inherited in an autosomal recessive manner. Affected infants have little or no retinal photoreceptor function as tested by electroretinography. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
Sequence similaritiesContains 1 PPIase FKBP-type domain.
Contains 3 TPR repeats.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- A930007I01Rik antibody
- Aipl1 antibody
- AIPL1_HUMAN antibody
Immunofluorescence of AIPL1 in Human brain tissue with ab79039 at 20 ug/mL.
Immunohistochemistry of Human brain tisue using ab79039 at 2.5 μg/ml.
Lane 1 : Anti-AIPL1 antibody (ab79039) at 1 µg/ml
Lane 2 : Anti-AIPL1 antibody (ab79039) at 2 µg/ml
All lanes : Human brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 44 kDa
Observed band size: 36 kDa why is the actual band size different from the predicted?
ab79039 has not yet been referenced specifically in any publications.