Overview

  • Product name
    Anti-AKR1B10 antibody
    See all AKR1B10 primary antibodies
  • Description
    Rabbit polyclonal to AKR1B10
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human AKR1B10.

    Read Abcam's proprietary immunogen policy

    (Peptide available as ab97989.)

  • Positive control
    • This antibody gave a positive signal in A549 whole cell lysate and Human small intestine tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab61832 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 36 kDa (predicted molecular weight: 36 kDa).

Target

  • Function
    Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
  • Tissue specificity
    Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
  • Sequence similarities
    Belongs to the aldo/keto reductase family.
  • Cellular localization
    Lysosome. Secreted. Secreted through a lysosome-mediated non-classical pathway.
  • Information by UniProt
  • Database links
    • Alternative names
      • AK1BA_HUMAN antibody
      • AKR1B10 antibody
      • AKR1B11 antibody
      • AKR1B12 antibody
      • Aldo keto reductase family 1 member B10 antibody
      • aldo keto reductase family 1 member B11 antibody
      • Aldo-keto reductase family 1 member B10 (aldose reductase) antibody
      • Aldo-keto reductase family 1 member B10 antibody
      • Aldo-keto reductase family 1 member B11 (aldose reductase-like) antibody
      • aldose reductase like 1 antibody
      • Aldose reductase like antibody
      • aldose reductase like peptide antibody
      • Aldose reductase related protein antibody
      • Aldose reductase-like antibody
      • Aldose reductase-related protein antibody
      • ALDRLn antibody
      • ARL 1 antibody
      • ARL-1 antibody
      • ARL1 antibody
      • ARL1 Human small intestine reductase antibody
      • ARP antibody
      • hARP antibody
      • HIS antibody
      • HSI antibody
      • SI reductase antibody
      • Small intestine reductase antibody
      see all

    Images

    • Western blot - Anti-AKR1B10 antibody (ab61832)
      Western blot - Anti-AKR1B10 antibody (ab61832)
      All lanes : Anti-AKR1B10 antibody (ab61832) at 1 µg/ml

      Lane 1 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell Lysate
      Lane 2 : Human small intestine tissue lysate - total protein (ab29276)

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

      Developed using the ECL technique.

      Performed under reducing conditions.

      Predicted band size: 36 kDa
      Observed band size: 36 kDa
      Additional bands at: 73 kDa. We are unsure as to the identity of these extra bands.


      Exposure time: 10 minutes

    References

    ab61832 has not yet been referenced specifically in any publications.

    Publishing research using ab61832? Please let us know so that we can cite the reference in this datasheet.

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