Product nameAnti-AKR1C1 antibody - C-terminal
See all AKR1C1 primary antibodies
DescriptionRabbit polyclonal to AKR1C1 - C-terminal
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse
- Human liver cancer, breast infiltrative duct and fetal brain tissue lysates. Human colon cancer tissue
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol, 49% PBS
PBS without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab183078 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200.|
|WB||1/500 - 1/2000. Predicted molecular weight: 37 kDa.|
FunctionConverts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Tissue specificityExpressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain.
Sequence similaritiesBelongs to the aldo/keto reductase family.
- Information by UniProt
- 2-dihydrobenzene-1 antibody
- 2-diol dehydrogenase antibody
- 20 alpha (3 alpha) hydroxysteroid dehydrogenase antibody
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue labeling AKR1C1 with ab183078 at a 1/30 dilution, in the presence (right panel) or absence (left panel) of immunizing peptide.
All lanes : Anti-AKR1C1 antibody - C-terminal (ab183078) at 1/500 dilution
Lane 1 : Human liver cancer tissue lysate
Lane 2 : Human breast infiltrative duct tissue lysate
Lane 3 : Human fetal brain tissue lysate
Lysates/proteins at 27 µg per lane.
All lanes : Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution
Developed using the ECL technique.
Predicted band size: 37 kDa
Exposure time: 2 minutes
ab183078 has not yet been referenced specifically in any publications.