Overview

  • Product name

    Anti-AKT2 antibody [EPR18211-280]
    See all AKT2 primary antibodies
  • Description

    Rabbit monoclonal [EPR18211-280] to AKT2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Sandwich ELISAmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes

    Anti-AKT2 antibody is used in our 90-minute Human, Mouse, Rat AKT2 ELISA Kit (ab208986), and is available in a Matched Antibody Pair Kit (ab216054).

Properties

Applications

Our Abpromise guarantee covers the use of ab222602 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use at an assay dependent concentration.

Target

  • Function

    General protein kinase capable of phosphorylating several known proteins.
  • Tissue specificity

    Expressed in all human cell types so far analyzed.
  • Sequence similarities

    Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 PH domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Phosphorylation on Thr-309 and Ser-474 is required for full activity.
    Ubiquitinated; undergoes both 'Lys-48'- and 'Lys-63'-linked polyubiquitination. TRAF6-induced 'Lys-63'-linked AKT2 ubiquitination. When fully phosphorylated and translocated into the nucleus, undergoes 'Lys-48'-polyubiquitination catalyzed by TTC3, leading to its degradation by the proteasome.
  • Information by UniProt
  • Database links

  • Alternative names

    • Akt2 antibody
    • AKT2_HUMAN antibody
    • HIHGHH antibody
    • Murine thymoma viral (v-akt) homolog 2 antibody
    • murine thymoma viral (v-akt) homolog-2 antibody
    • Oncogene AKT2 protein kinase B beta antibody
    • PKB antibody
    • PKB beta antibody
    • PKBB antibody
    • PKBBETA antibody
    • PRKBB antibody
    • Protein kinase Akt 2 antibody
    • Protein kinase Akt-2 antibody
    • Protein kinase B beta antibody
    • RAC beta antibody
    • rac protein kinase beta antibody
    • RAC-BETA antibody
    • RAC-beta serine/threonine-protein kinase antibody
    • RAC-PK-beta antibody
    • RACbeta antibody
    • v akt murine thymoma viral oncogene homolog 2 antibody
    • V-AKT murine thymoma viral oncogene homolog 2 antibody
    see all

Images

  • Example of mouse AKT2 standard curve in 1X Cell Extraction Buffer PTR using recombinant AKT2 RabMAb antibody (ab222602) and a recombinant monoclonal antibody. Background-subtracted values (mean +/- SD) are graphed.

    For a complete ELISA kit, see AKT2 ELISA kit (ab208986).

    For a matched antibody pair set, see AKT2 Matched Antibody Pair Kit (ab216054).

References

ab222602 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab222602.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up