Recombinant
RabMAb

Recombinant Anti-ALAD antibody [EPR10269(B)] (ab151697)

Overview

  • Product name

    Anti-ALAD antibody [EPR10269(B)]
    See all ALAD primary antibodies
  • Description

    Rabbit monoclonal [EPR10269(B)] to ALAD
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human ALAD aa 250-350. The exact sequence is proprietary.

  • Positive control

    • Human red blood cell and fetal liver lysates.
  • General notes

    Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20ºC.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR10269(B)
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab151697 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 36 kDa.
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function

      Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
    • Pathway

      Porphyrin metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.
    • Involvement in disease

      Defects in ALAD are the cause of acute hepatic porphyria (AHP) [MIM:612740]. AHP is a form of porphyria. Porphyrias are inherited defects in the biosynthesis of heme, resulting in the accumulation and increased excretion of porphyrins or porphyrin precursors. They are classified as erythropoietic or hepatic, depending on whether the enzyme deficiency occurs in red blood cells or in the liver. AHP is characterized by attacks of gastrointestinal disturbances, abdominal colic, paralysis, and peripheral neuropathy. Most attacks are precipitated by drugs, alcohol, caloric deprivation, infections, or endocrine factors.
    • Sequence similarities

      Belongs to the ALADH family.
    • Information by UniProt
    • Database links

    • Alternative names

      • ALAD antibody
      • ALADH antibody
      • ALADR antibody
      • Aminolevulinate dehydratase antibody
      • Aminolevulinate, delta, dehydratase antibody
      • Delta aminolevulinic acid dehydratase antibody
      • Delta-aminolevulinic acid dehydratase antibody
      • HEM2_HUMAN antibody
      • Lv antibody
      • MGC5057 antibody
      • OTTMUSP00000009376 antibody
      • OTTMUSP00000009377 antibody
      • PBGS antibody
      • Porphobilinogen synthase antibody
      • RP11-10I9.1 antibody
      • RP24-189G18.9 antibody
      see all

    Images

    • All lanes : Anti-ALAD antibody [EPR10269(B)] (ab151697) at 1/1000 dilution

      Lane 1 : Human red blood cell lysate
      Lane 2 : Human fetal liver lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 36 kDa

    References

    ab151697 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab151697.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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