Key features and details
- Chicken polyclonal to Albumin
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgY
Product nameAnti-Albumin antibody
See all Albumin primary antibodies
DescriptionChicken polyclonal to Albumin
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Synthetic peptide corresponding to Human Albumin (internal sequence). The immunogen is located within amino acids 340 - 390 of Albumin.
Database link: P02768
- Mouse liver lysate; Human liver tissue
Antibodies should not be exposed to prolonged high temperatures.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Please see notes section.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106582 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 69 kDa.|
|IHC-P||Use a concentration of 2.5 - 20 µg/ml.|
|IF||Use a concentration of 20 µg/ml.|
FunctionSerum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
Involvement in diseaseDefects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
Sequence similaritiesBelongs to the ALB/AFP/VDB family.
Contains 3 albumin domains.
modificationsKenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
Glycated in diabetic patients.
Phosphorylation sites are present in the extracelllular medium.
Acetylated on Lys-223 by acetylsalicylic acid.
- Information by UniProt
FormThere are 2 isoforms produced by alternative splicing.
- alb antibody
- ALBU_HUMAN antibody
- Albumin (32 AA) antibody
Lane 1 : Anti-Albumin antibody (ab106582) at 1 µg/ml
Lane 2 : Anti-Albumin antibody (ab106582) at 2 µg/ml
All lanes : Mouse liver tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 69 kDa
Immunohistochemical analysis of paraffin embedded Human liver tissue section labelling Albumin with ab106582 at 2.5 µg/ml.
Immunohistochemical analysis of paraffin embedded Mouse liver tissue section labelling Albumin with ab106582 at 5 µg/ml.
Immunofluorescence analysis of paraffin embedded mouse liver tissue section labelling Albumin with ab106582 at 20 µg/mL.
ab106582 has been referenced in 35 publications.
- Dong S et al. Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo. Nat Commun 11:645 (2020). PubMed: 32005807
- Tan Z et al. Neuroprotective effects of FK866 against traumatic brain injury: Involvement of p38/ERK pathway. Ann Clin Transl Neurol 7:742-756 (2020). PubMed: 32302063
- Kitchen P et al. Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema. Cell 181:784-799.e19 (2020). PubMed: 32413299
- Zhang H et al. Hypertonic saline improves brain edema resulting from traumatic brain injury by suppressing the NF-?B/IL-1ß signaling pathway and AQP4. Exp Ther Med 20:71 (2020). PubMed: 32963601
- Ko HJ et al. GSKIP-Mediated Anchoring Increases Phosphorylation of Tau by PKA but Not by GSK3beta via cAMP/PKA/GSKIP/GSK3/Tau Axis Signaling in Cerebrospinal Fluid and iPS Cells in Alzheimer Disease. J Clin Med 8:N/A (2019). PubMed: 31640277