Recombinant
RabMAb

Anti-Albumin antibody [EPSISR1] (ab137885)

Overview

  • Product name
    Anti-Albumin antibody [EPSISR1]
    See all Albumin primary antibodies
  • Description
    Rabbit monoclonal [EPSISR1] to Albumin
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-P, Flow Cytmore details
    Unsuitable for: ICC or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Albumin aa 50-150. The exact sequence is proprietary.
    (Peptide available as ab190884)

  • Positive control
    • Human serum lysate; Human fetal liver lysate; Human liver tissue; Human lung tissue
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab137885 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 69 kDa.
IHC-P 1/250 - 1/500.
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

  • Application notes
    Is unsuitable for ICC or IP.
  • Target

    • Function
      Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
    • Tissue specificity
      Plasma.
    • Involvement in disease
      Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.
    • Sequence similarities
      Belongs to the ALB/AFP/VDB family.
      Contains 3 albumin domains.
    • Post-translational
      modifications
      Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.
      Glycated in diabetic patients.
      Phosphorylation sites are present in the extracelllular medium.
      Acetylated on Lys-223 by acetylsalicylic acid.
    • Cellular localization
      Secreted.
    • Information by UniProt
    • Database links
    • Form
      There are 2 isoforms produced by alternative splicing.
    • Alternative names
      • alb antibody
      • ALBU_HUMAN antibody
      • Albumin (32 AA) antibody
      • Albumin (AA 34) antibody
      • cell growth inhibiting protein 42 antibody
      • DKFZp779N1935 antibody
      • GIG20 antibody
      • GIG42 antibody
      • growth-inhibiting protein 20 antibody
      • OTTHUMP00000220436 antibody
      • OTTHUMP00000220438 antibody
      • OTTHUMP00000220439 antibody
      • PRO0883 antibody
      • PRO0903 antibody
      • PRO1341 antibody
      • PRO1708 antibody
      • PRO2044 antibody
      • PRO2619 antibody
      • PRO2675 antibody
      • Serum albumin antibody
      • UNQ696/PRO1341 antibody
      see all

    Images

    • Immunohistochemical analysis of paraffin-embedded Human liver tissue labelling Albumin with ab137885 at 1/250 dilution.
    • Immunohistochemical analysis of paraffin-embedded Human lung tissue labelling Albumin with ab137885 at 1/250 dilution.
    • All lanes : Anti-Albumin antibody [EPSISR1] (ab137885) at 1/1000 dilution

      Lane 1 : Human serum lysate
      Lane 2 : Human fetal liver lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 69 kDa

    References

    This product has been referenced in:
    • Peng YC  et al. Combination of 5-fluorouracil and 2-morphilino-8-phenyl-4H-chromen-4-one may inhibit liver cancer stem cell activity. Tumour Biol N/A:N/A (2016). Human . Read more (PubMed: 26886287) »
    • Wang J  et al. Identification of a distinct small cell population from human bone marrow reveals its multipotency in vivo and in vitro. PLoS One 9:e85112 (2014). WB . Read more (PubMed: 24465489) »

    See all 2 Publications for this product

    Customer reviews and Q&As

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